Sentences with phrase «researchers tested the animals»

Not exact matches

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

The researchers are excited by the results and their next step is to test the structures in larger animals.

The researchers caution that the booster therapy used in their new study will not be available on the market or even for use in human trials anytime soon; it must await years of animal testing for safety and effectiveness first.

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

In medicine today, physician - scientists and basic scientists supplement support for their research by applying their expertise part time to develop and test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and animal model development performed for pharmaceutical and instrument companies.

When the young animals were successfully weaned, researchers gave them a series of tests to gauge their fear response, along with their cognitive, memory and social skills.

In subsequent studies the researchers plan to analyze further relevant datasets in order to test different scenarios of the evolution of the earliest animal phyla.

The researchers put the mice through a standard test in which the animals are trained to find a platform in a swimming pool.

The compound, already proven safe for humans, is undergoing further animal testing in preparation for possible clinical trials in cocaine addicts, the researchers say.

Testing heritability is easier in laboratory conditions because all the animals are raised in the same environment and the researchers know the relatedness of all the lizards, Cox said.

The researchers tested what the webs could catch in the most direct way possible: by lobbing different prey animals at them from half a metre away.

To develop the test, the researchers targeted unique stretches of DNA or RNA from every known group of viruses that infects humans and animals.

Stress can affect a wide range of physiologies and behaviors, and researchers are beginning to test whether the additions make the animals better models for depression — and, in the case of these particular fish — retinal regeneration.

Besides its potential application in human patients, the newly developed skin tissue also could be used as an alternative to testing cosmetics on animals, the researchers said.

Even as researchers test these findings in animals, Nabel's team is exploring an intriguing possibility: adding the Ebola virus membrane protein to a harmless virus that could then carry therapeutic genes specifically to endothelial cells.

Researchers performed a meta - analysis of literature examining patients with NASH, and then tested their hypothesis using an animal model, which enabled them to eliminate possible confounders of the clinical data, such as antibiotic exposure and medical comorbidities.

This quandary has inspired some researchers to add macaques as test subjects, although those animals are not void of drawbacks, either.

The UCLA researchers plan to develop strategies to test the Duchenne - specific CRISPR / Cas9 platform to treat the disease in animals as the next step toward perfecting a method that can be used in humans.

This past spring, Peersen received a new National Institutes of Health grant to continue testing the genetic modification in live animals, in partnership with researchers at the University of Wisconsin.

The deficient animals, for example, gave up more easily in a classic forced swimming test, were less inclined to explore, and were more inclined to stay near the wall of a cage, «a widely accepted index of anxiety,» the researchers noted in their study.

In the past, researchers have examined herbal medicines by running assays for toxic compounds and using DNA tests to determine whether a specific plant or animal is present.

Biologists now think they understand why: In laboratory tests, torn bay leaves turned out to be very toxic to fleas, researchers reported last week at a meeting of the Animal Behavior Society in Carbondale, Illinois.

Researchers at Scripps and other institutions began testing blood samples from these individuals in animals and found that they were producing broadly neutralizing antibodies capable of eliminating most of the HIV varieties, says Crotty.

The paper is «a big step forward» because running such tests in the wild «is exceptionally challenging,» says Alex Thornton, an animal cognition researcher at the University of Exeter in the United Kingdom.

Finally, the researchers tested this circuitry in live animals, artificially turning on the motor neurons in anesthetized mice and then looking to see how the auditory cortex responded.

The researchers, who evaluated the BSCB in test animals at seven and 30 days after stroke modeling, found that ischemic stroke damaged the gray and white matter in the cervical spinal cord on both sides of the spinal column, based on analysis of electron microscope images.

The researchers now plan to test this type of insulin in other animal models and are also working on tweaking the chemical composition of the insulin to make it even more responsive to blood - glucose levels.

In a verdict that U.K. scientists see as a turning point in efforts to protect animal researchers against illegal attacks, a British court yesterday convicted four people of conspiring to blackmail companies that supply an animal testing laboratory.

To explore the function of the animals» trilling calls in the new study, the researchers tested the ability of human listeners to detect subtle differences in synthetic calls.

The results need be tested and confirmed in animal studies before researchers can be sure that HtrA1 is the link between ApoE4 and Alzheimer's in humans.

The researchers found that, in test animals, modification of the blood - forming stem cells resulted in more than two years of stable production of CAR - expressing cells without any adverse effects.

The researchers plan to perform further tests on lab animals to assess the fake cells» long - term health effects before running clinical trials.

Researchers all over Europe are working on alternatives to animal testing that can be used to evaluate the adverse side - effects of medications.

Using DNA strands just 58 nucleotides long to uniquely identify each particle allows researchers to skip the cell culture screening altogether — and test a hundred or more different types of nanoparticles simultaneously in just a handful of animals.

However, none of the supplements worked very well in animals, even when researchers administered them in repeated, high doses for a month prior to a noise - exposure test, Le Prell notes.

As next steps, the researchers would like to test their hydrogel matrix in animals with normal immune systems and in disease models.

The researchers used a computer program to test the possible evolutionary bushes that could have yielded cetaceans along with artiodactyls — the mammalian order made up of two - toed, hoofed animals — which include Indohyus and hippos.

Traditionally, researchers then disable or «knock out» the gene in lab - grown cells or animals to test their hypothesis, a time - consuming and laborious process.

The researchers also implanted untreated — or «as - cast» — alloy, finding that both the as - cast samples and T - 5 heat - treated alloys showed good biocompatibility and promoted bone growth in test animals.

For the animals that were born in 2014, the researchers also measured the level of confidence exhibited by the animals using a so - called stick test.

Moving their studies from cells to whole animals, the researchers tested the effects of knocking out the Zbp1 gene in mice infected with influenza.

MERS and SARS: The pause includes three grants and two contracts that are attempting to develop a strain of the MERS coronavirus that sickens mice so that researchers will have an animal model for testing MERS drugs and vaccines.

Researchers still need to test the treatment in animals, which could take several years.

The researchers examined respondents» deference to science on a scale of 0 - 10 when it came to 14 policy issues, including child vaccinations, stem cell research, global warming, child obesity and diet, AIDS prevention, birth control education, legalizing drug use, gun control, regulation of nuclear power, animal testing, and teaching evolution in schools.

Better drugs could provide relief, but before giving new medicines to people, researchers must first test them in animals — a costly and laborious process.

In some prior work with related systems in animal tests, OSU and collaborating researchers have been able to completely eradicate tumors.

Researchers say the next step is to test whether small ingots of metal in seawater consistently repel animals in the lab.

Camels: Following a lead that some early MERS victims were in contact with camels, researchers tested 50 of the animals from nearby Oman: All had antibodies showing previous exposure to MERS, according to another study published in August.

The researchers initially tested proliposomal ropivacaine in pigs, showing that it gradually released ropivacaine into the animals» circulation.

To test this idea, the researchers examined the animals» ability to open a box without prior demonstration by a dog.