Now Yi - Yun Liu at the South China Agricultural University in Guangzhou and colleagues have discovered the first known
resistance gene for colistin that is able to move freely from one bacterium to another.
«This knowledge will facilitate identification and isolation of additional
resistance genes for improved control of Septoria,» adds Kanyuka.
The scientists have also detected
resistance genes for sulphonamides and another antibiotic in the treated wastewater — which will be turned into snow at a nearby ski resort, in a relatively pristine part of a river basin, later this year.
Not exact matches
I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions
for preventing infections in some common surgeries, tackling
resistance in targeted antibody drugs, improving
gene vectors
for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.
Scientists could search within them
for resistance genes and other desirable traits to use in engineering and breeding programs.
At the
gene level, traditional and adapted seeds and breeds are preferred
for their greater
resistance to diseases and their resilience to climatic stress.
«We think that the garter snake's evolved
resistance to the newt's toxin can be used as a model
for understanding complex adaptations that involve more than one
gene,» McGlothlin said.
We identified some specific
resistance genes that code
for receptor - like proteis (RLPs) and described how they operated against the pathogens.
The bacteria behind gonorrhoea readily acquire
genes for resisting drugs and so from 2012, UK patients were given two antibiotics at once — azithromycin pills plus a ceftriaxone injection — so if bacteria acquired
resistance to one, they would be killed by the other.
Professor Bruce Fitt, professor of plant pathology at the University of Hertfordshire, added: «This new understanding of plant defense through ETD suggests different operations of specific
resistance genes which will help us to be more successful in breeding new strains of crops
for resistance.
But they lost some things in the process, like
genes for disease
resistance that still occur in wild peanut ancestors.
They hope to identify the
genes and mechanisms responsible
for aflatoxin
resistance.
«We're also looking at as many
genes as possible in the wild banana and screening them to identify other
resistance genes, not only
for resistance to TR4 but to other diseases.»
A 2003 study of the mouths of healthy kindergartners found that 97 percent harbored bacteria with
genes for resistance to four out of six tested antibiotics.
Bacteriophages, or viruses that infect bacterial pathogens, may also act as vectors of virulence or of antibiotic
resistance genes, ultimately making bacterial disease worse
for the host.
Over the past 60 years,
genes for antibiotic
resistance have gone from rare to commonplace in the microbes that routinely infect our bodies.
But the rapid rise of bacterial
genes for drug
resistance stems from more than lucky mutation, Levy adds.
The Sainsbury Laboratory is continuing to identify multiple blight
resistance genes that will difficult
for blight to simultaneously overcome.
«You've got the
genes encoding
for resistance in the soil beneath these operations,» he says, «and we know that the majority of the antibiotics animals consume get excreted intact.»
As a marker
for successful insertion, the researchers also put a
gene encoding antibiotic
resistance into the plasmid.
The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced Cell Technology in Worcester, Massachusetts — inserted a marker
gene fused with a
gene for resistance to the chemical neomycin into a culture of connective tissue cells called fibroblasts.
But they also collected wild relatives of chickpeas in southeastern Turkey that hold «great promise,» von Wettberg says, as a source of new
genes for traits like drought -
resistance,
resistance to pod - boring beetles, and heat tolerance.
Genes that code
for resistance to antibiotics existed even before we discovered and started using antibiotics.
The activity of four transcription factors — proteins that regulate the expression of other
genes — appears to distinguish the small proportion of glioblastoma cells responsible
for the aggressiveness and treatment
resistance of the deadly brain tumor.
The answer is that it forms the platform
for illuminating the interaction between the use of animal manure and the appearance of
genes for antibiotic
resistance in soil.
And the
genes needed
for resistance may take their own toll, perhaps by shortening a mosquito's life span.
So even if you start off [with] say, a resistant type of staph infection, that line of staph organisms not only, will they be more resistant, but they may pass some of the
genes for that
resistance off to completely other unrelated types of bacteria.
New research presented here yesterday at the annual meeting of the American Association
for the Advancement of Science (which publishes ScienceNOW) finds that a
gene associated with increased risk of asthma is also linked to
resistance against a parasitic worm.
She doubts,
for instance, the suggestion that weeds could be
gene - drive engineered to eliminate herbicide
resistance.
The first transgenic crop likely to be put forward
for approval
for open trials and commercial release is Bt cotton — which has added
genes from the Bacillus thuringiensis bacterium, making the plant produce toxins that confer
resistance to some insect pests.
The number of copies of the
resistance gene varies among cultivars; a new method, developed by University of Illinois researchers, is able to efficiently quantify this variation
for the first time.
«
Genes may cause tumor aggressiveness, drug
resistance in African - American prostate cancer: Research found many targeted therapies
for prostate cancer may not be effective against tumors in African - American men.»
A plasmid, a simple kind of DNA - delivery vehicle, will move a
gene for antibiotic
resistance into the bacterial cells, jump - starting the Crispr - Cas9 system.
So, it's not an issue of her possibly becoming infected by these parasites, but because there is usually a genetic basis [
for] parasite
resistance, she may be looking
for good
genes for her offspring to survive better.
For more than 30 years, scientists have proposed that
resistance genes actually originate from the microorganisms producing the antibiotic.
We could get radiation -
resistance genes,
for example, from the Bdelloid rotifer, a class of small invertebrates that live in freshwater pools and survive megadoses of ionizing radiation.
And the race is on to find a molecular marker
for PPQ
resistance, the equivalent of the K13
gene.
One reservoir
for resistance genes where they can be exchanged among bacteria — and possibly end up in the food chain — is the sediment in marine fish farms even when no antibiotics have been applied.
The effort has already had one practical result: the discovery of two new
genes for resistance to a race of wheat stem rust to which there is virtually no
resistance in wheat.
From isolated caves to ancient permafrost, antibiotic - resistant bacteria and
genes for resistance have been showing up in unexpected places.
The
gene for colistin
resistance can be easily spread to other bacteria, making it likely that colistin
resistance will become widespread in the future.»
And determining treatment strategies will be no less complex: Last summer,
for example, a team of scientists linked 124 different
genes to
resistance to four leukemia drugs.
How many different
genes for antibiotic
resistance come to Israel from the various dust storms, and how prevalent are these
genes?
Although many different malaria
resistance loci have been postulated over the years, this is one of very few that have stood up to stringent testing in a large multi-centre study; the others include the
genes for sickle cell and the O blood group.
«This new
resistance locus is particularly interesting because it lies so close to
genes that are gatekeepers
for the malaria parasite's invasion machinery.
The former target, say, using
gene editing techniques to inactivate HIV receptors and achieve
resistance of blood cells to the virus (which Sangamo BioSciences is working on in clincial trials) is different than helping parents who both carry
genes for Huntington's Disease to have a child that is free of the disease (a change to the genome that would be passed on to future generations and would likely not be very commonly needed).
One species, Glycine tomentella, was of particular interest because it has
genes for resistance to soybean rust and to soybean cyst nematode, he said.
She has tracked dramatic increases in the prevalence of several
genes and suites of
genes coding
for drug
resistance.
The team cut and pasted a bovine
gene for NRAMP1, a protein linked to
resistance against TB and other bacterial infections, into fetal dairy cow genomes.
But bacteria can pass on the
genes for antibiotic
resistance, so any source of
resistance is concerning.