Using mass DNA sequencing, he recently identified
resistance genes even in bacteria in pristine permafrost and deep caves.
Not exact matches
Microbes could load these donated
genes together on a single piece of DNA, accelerating the spread of
resistance even further.
Genes that code for
resistance to antibiotics existed
even before we discovered and started using antibiotics.
So
even if you start off [with] say, a resistant type of staph infection, that line of staph organisms not only, will they be more resistant, but they may pass some of the
genes for that
resistance off to completely other unrelated types of bacteria.
One reservoir for
resistance genes where they can be exchanged among bacteria — and possibly end up in the food chain — is the sediment in marine fish farms
even when no antibiotics have been applied.
Even in the half or so of all diabetes cases that seem to be related to
genes that have programmed a person's cells to need less fuel, exercise and moderate diet changes can work wonders if the progress of insulin
resistance is noticed soon enough during regular checkups.
Three - quarters of them contained the genetic material of one or
even two copies of a pesticide
resistance gene called ace - lR.
With a human strain showing widespread
resistance as well — and the fact that pandemic viruses may arise when avian and human strains swap
genes — makes it
even less appealing, says Bright.
But many of the microbes Chénier's team studied harbored a chlortetracycline
resistance gene on plasmids,
even after years without the antibiotic.
However, researchers from the Universities of Reading and Oxford have found some rats that seem to suffer none of the disadvantages that usually accompany the
gene for
resistance, and may
even have an advantage over the susceptible animals.
A few years later, O'Neill and others made a startling discovery: They didn't
even need to couple Wolbachia to infection
resistance genes.
«
Even though the specific molecular changes that are found in PCB - resistant tomcod and killifish are different, in both species AHR2 seems to be one of the
genes — possibly the major
gene — that is responsible for the
resistance,» Hahn said.
«For all of the bacteria we tested, their conjugation rate is sufficiently fast that,
even if you don't use antibiotics, the
resistance can be maintained —
even if the
genes carry a high cost.»
It may take as long to breed a new
resistance gene into a new cultivar as to introduce a new fungicide (± 10 years),
even though this time can be shortened somewhat today with molecular tools by reducing the back - crossing cycles.
If the chicken coops of subsistence farmers are hot spots of
resistance gene transfer, he speculated that bacteria present in industrial farming operations — where chickens regularly receive antibiotics — would see
even more pressure to share
resistance genes.
Bacteria can acquire
resistance by getting a copy of a
gene encoding an altered protein or an enzyme like beta lactamase from other bacteria,
even from those of a different species.
Monitoring parasite populations for a specific genetic background — in this case, a fixed set of four well - defined mutations in the fd, arps10, mdr2, and crt
genes — could allow researchers to assess the likelihood of new
resistance - causing mutations emerging in different locations, helping to target high - risk regions
even before resistant parasites take hold.
The next step will be to stack these two
genes to determine if they can work synergistically and enhance blight
resistance even higher.
A doctor may not
even be giving vancomycin, but vancomycin
resistance increases because the
genes happen to be grouped together.
Even if a specific defense
gene enables the plant to detect and stop an infection, the pathogen can evolve a new strategy to overcome the plant's
resistance.
«Our study demonstrates that
even well - studied bacteria — the ones that we know cause disease or their close relatives — have many
genes associated with antibiotic
resistance that have not been characterized before,» said senior author Gautam Dantas, PhD, associate professor of pathology and immunology.
The company website says the test is highly accurate for detecting degenerative myelopathy, exercise - induced collapse, PRA blindness, dilated cardiomyopathy, and
even multi-drug
resistance gene sensitivity.