The phrase
"resistant infections" refers to infections caused by bacteria or germs that cannot be treated effectively with certain medicines or drugs because they have adapted or developed resistance to them.
Full definition
As you can see from the infographic above, which is included in the report, the use of antibiotics in farm animals leads to an increased risk of antibiotic
resistant infections in humans.
Current clinical options for treating
antibiotic resistant infections include increasing the prescribed antibiotic dose or using a combination therapy of two or more antibiotics.
Drug -
resistant infections kill an estimated 700,000 people each year according to a recent report on this issue commissioned by the British government.
The investigators also found that young people with antibiotic -
resistant infections stayed in the hospital 20 percent longer than those whose infections could be addressed by antibiotics.
In theory, a database of recovery times for bacterial and antibiotic combinations could allow first - line antibiotics to clear
many resistant infections.
Over the past decade, the US Centers for Disease Control and Prevention reported a substantial increase in incidence of opportunistic premise plumbing pathogens, with Pseudomonas alone accounting for 51,000 hospitalizations per year with more than 6,000
multi-drug resistant infections in 2011.
A follow - up study found that the same strain, dubbed «clonal group A,» also caused about 40 %
of resistant infections in two smaller study sites in Ann Arbor, Michigan, and Minneapolis, Minnesota.
With bacteria evolving to resist antibiotics faster than scientists can concoct new drugs, the fight
against resistant infections in hospitals and food supplies is a tough battle to win.
According to the Centers for Disease Control, more than two million people come down with antibiotic -
resistant infections annually, and at least 23,000 die because their treatment can't stop the infection.
If a bacterial population can become antibiotic - resistant even when only a small number of individuals have the appropriate genetic mutations, doctors who collect and analyze small bacterial specimens from patients may underestimate just
how resistant the infection is as a whole, Collins notes.
Tim Jinks, Head of Drug -
Resistant Infections at Wellcome, said: «E. coli are the leading cause of bloodstream infections and this study helps illustrate the incredible complexity of the acquisition and spread of multidrug - resistant strains.
Although the cost of antibiotic -
resistant infection treatment has exceeded $ 2 billion annually, the CDC says we can control it with more rigorous testing in health care facilities.
A version of this article appears in print on September 17, 2013, on Page A13 of the New York edition with the headline: Antibiotic -
Resistant Infections Lead to 23,000 Deaths a Year, C.D.C. Finds.
This indicates that existing antibiotics may be more effective against drug -
resistant infections if used in combination with manuka honey.»
Some 23,000 people die every year in the U.S.
from resistant infections, with health care costs projected up to $ 20 billion.
Similarly, some $ 10.6 million of a $ 12.2 million increase starting next year in the $ 782 - million - a-year budget of the Canadian Institutes of Health Research is pegged for health care efficiency and effectiveness research, with the rest focused on «the health challenges posed by
anti-microbial resistant infections.»
As the fight against drug -
resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics.
That's because the genes sit on a mobile chunk of DNA that can be acquired by many species of bacteria, increasing the incidence of drug -
resistant infections such as the E. coli outbreak last year in Germany.
With antibiotic -
resistant infections currently responsible for 50,000 deaths per year in the United States and Europe alone, the results of this study suggest that further research is needed to help combat overuse.
The research, published in the March issue of the Journal of the Pediatric Infectious Diseases Society, is the first known effort to comprehensively examine the problem of multi-drug
resistant infections among patients under 18 admitted to US children's hospitals with Enterobacteriaceae infections.
Anti-microbial resistance is a growing threat, with 700,000 people around the world each year dying due to drug -
resistant infections including tuberculosis, HIV and malaria.
The effect this would have
on resistant infections in people is difficult to forecast, because resistance arises in both farm animals and people.
«We need to make sure the genes that make these strategies possible aren't shared with infectious bacteria, because they could make the problem of drug -
resistant infections much worse.»
The discovery of an effective combination therapy has the potential to change medical practice for the treatment of the drug
resistant infections which the World Health Organization (WHO) last week identified as of «critical priority» for their threat to human health.
UC San Diego Health System recently celebrated Food Day by serving antibiotic - free beef and poultry as part of a national effort to raise awareness of antibiotic -
resistant infections linked to the food we eat.
In part, fewer broad - spectrum antibiotics suitable for children can mean more antibiotic -
resistant infections go untreated, according to Meropol.
Although weak or underdeveloped immune systems partly explain younger children's vulnerability, the association
between resistant infections and older ages is more difficult to explain, Meropol said.
Hospital acquired
methicillin resistant infections can readily be transmitted from patient to patient in the hospital, and preventing transmission is one reason veterinarians and physicians wash and sanitize their hands between patients.
Some scientists are even exploring the role of raw honey in treating antibiotic -
resistant infections like MRSA, VRE, MDR - TB, and CRE.
A
multi-drug resistant infection that can cause life - threatening illness in people with cystic fibrosis (CF) and can spread from patient to patient has spread globally and is becoming increasingly virulent, according to new research published today in the journal Science.
We utilize a combination of structural biology, biochemistry, and cell biology to determine the unique and critical protein and nucleic acid components in these pathways that can be targeted for new therapeutic strategies aimed at
drug resistant infections.
«Most antibiotics have their effect, directly or indirectly, by causing damage to bacterial DNA, so finding ways to cripple DNA repair would represent a significant advance in the treatment
of resistant infections,» says senior study author Evgeny Nudler, PhD, the Julie Wilson Anderson Professor of Biochemistry, Department of Biochemistry and Molecular Pharmacology, NYU Langone.
NIAID researchers and colleagues sought to confirm the presence of piperaquine -
resistant infections in Cambodia by comparing the efficacy of dihydroartemisinin - piperaquine treatment in 204 malaria - afflicted participants aged 2 to 65 years from three provinces in Cambodia with varying levels of artemisinin resistance.
Phrases with «resistant infections»