As you can see from the infographic above, which is included in the report, the use of antibiotics in farm animals leads to an increased risk of antibiotic
resistant infections in humans.
A clinical trial to evaluate whether the ointment can treat antibiotic
resistant infections in human patients is scheduled for 2018.
Not exact matches
What's more, an ointment containing the peptide effectively treated wounds infected with methicillin -
resistant Staphylococcus aureus (MRSA) and the increasingly common hospital
infection bacterium Acinetobacter baumannii
in mice and on laboratory samples of
human skin.
Pseudomonas aeruginosa is usually harmless to
humans, but
in people with cystic fibrosis (CF) or who have weakened immune systems — such as those who have had an operation or treatment for cancer — it can cause
infections that are
resistant to antibiotics.
ST258 K. pneumoniae is the predominant cause of
human infections among bacteria classified as carbapenem -
resistant Enterobacteriaceae (CRE), which kill approximately 600 people annually
in the United States and sicken thousands more.
Or perhaps the answer lies
in the interplay between the immune system and
human genetic variability: Studies have highlighted genes that strongly influence who is most susceptible — and who is most
resistant — to HIV
infection and disease.
To explore the health consequences of bacterial quorum sensing
in the crypts, the researchers experimented with an antagonist to turn off quorum sensing
in chambers colonized by methicillin -
resistant S. aureus (MRSA), an antibiotic -
resistant strain of bacteria that causes
human infection.
Chinese researchers report this week that they have used the CRISPR gene - editing technique to modify the genome of a
human embryo
in an effort to make it
resistant to HIV
infection.
Researchers
in China have reported editing the genes of
human embryos to try to make them
resistant to HIV
infection.
Because mice with intact immune systems are
resistant to S. stercoralis
infection, the researchers began with an immunocompromised strain of mice, and then exposed some to a synthetic steroid called methylprednisolone (MPA) that is commonly used to treat asthma
in humans.
Researchers
in China have edited the genes of
human embryos to make cells
resistant to HIV
infection.
In this study we describe the design and pre-clinical evaluation of a CXCR4 - specific ZFN pair (X4 - ZFNs) that specifically and efficiently disrupts cxcr4, rendering
human CD4 + T cells permanently
resistant to HIV - 1 strains that require CXCR4 for
infection.
Our studies provide a fundamental demonstration that inactivation of cxcr4 by treatment with X4 - ZFNs rendered
human CD4 + T cells
resistant to
infection by X4 virus strains, while CXCR4 inactivation
in the context of a ccr5Δ32 homozygous background rendered cells
resistant to
infection by both R5 and R5X4 strains.
This concern was also brought to the forefront of the scientific and public consciousness when a report by Chinese scientists described the use of CRISPR - Cas to modify a gene
in human embryos making them
resistant to HIV
infection [to learn more about CRISPR - Cas, read our previous blog].
In the
resistant infections, the communication system used by MRSA bacteria to «talk» among each other is silenced, and with it the ability to release toxins that damage
human cells.
Infection with
resistant organisms can lead to longer and more severe
infections, increased mortality, and higher costs for treatment.1, 2 The growing threat of AMR has contributed to an increased scrutiny of antibiotic use practices
in both
human and veterinary medicine (FIGURE 1).
Adult
humans usually are
resistant to
infection unless there is a break
in the skin (such as a scratch), but children are quite susceptible.
Natural resistance Healthy
humans, cats, and other species are by nature quite
resistant to
infection - so
resistant,
in fact, that if a person becomes infected with the fungus, it always heralds the need to look for some underlying disorder of the immune system (such as AIDS and certain forms of cancer).
Healthy adult
humans are usually
resistant to
infection unless there is a break
in the skin such as a scratch.
Chalk up yet another reason to oppose factory farming: BBC News reports that scientists from the University of Hong Kong have found evidence that overuse of antibiotics on farm animals is leading to an increase
in antibiotic -
resistant human urinary tract
infections.