Are there any indications (from Europe or any North American populations) that there are
resistant subpopulations?
These samples had previously been sequenced and genotyped through the MalariaGEN P. falciparum Community Project and assigned to artemisinin - sensitive or artemisinin -
resistant subpopulations in the analysis described in Miotto et al (2013).
Hence, BH3 mimetics might represent an attractive approach of eliminating
resistant subpopulations of cancer cells, thereby targeting both tumor cell invasion and cancer relapse.
Resistant cells among the separate replicates would contain the same labels - i.e. they would always come from the same parent cells that represent the preexisting
resistant subpopulation