Sinclair's lab is now working on developing what he calls a possible «supermouse» with elevated levels of NAMPT to see if it lives longer and is more disease -
resistant than normal mice.
Not exact matches
Both groups of animals are more
resistant to insulin
than normal mice are, the researchers discovered.
On the flip side, said Tran, PGC1 alpha transgenic
mice, which had increased expression of these genes, were particularly
resistant to various stressors and recovered from injury much more
than quickly
than animals with
normal regenerative abilities.
The older
mice fed a diet containing extra amounts of vitamin E, the equivalent to about 200 IU / day consumed by humans — about 10 times the Recommended Daily Allowance but well below the upper limit — were far more
resistant to the bacteria
than the older
mice that had a
normal amount of vitamin E in their diet.
mouse studies, macrophages taken from obese
mice were less receptive to insulin
than normal (in other words insulin
resistant to a degree).