The project that is farthest along involves the discovery of small molecules for use in combination with drugs of last resort for extensively drug -
resistant tuberculosis infections.
Not exact matches
They found that 43.7 % of the study participants were infected with a
tuberculosis strain that was
resistant to at least one second - line drug, and 6.7 % of the
infections proved to be XDR
tuberculosis.
Even if we prevent new drug -
resistant infections, there are enough current cases to keep the epidemic going, and drug -
resistant tuberculosis will continue to be an increasingly dangerous threat so long as
resistant strains spread through the air from one person to another,» says Dr Sharma.
This extensively drug -
resistant (XDR)
tuberculosis heralds a disturbing trend towards
infections that are virtually untreatable.
Anti-microbial resistance is a growing threat, with 700,000 people around the world each year dying due to drug -
resistant infections including
tuberculosis, HIV and malaria.
Mice infected with a
resistant strain of
tuberculosis that were treated with both SMARt - 420 and ethionamide also showed a significantly reduced bacterial load in their lungs three weeks after
infection compared to controls, the authors report.
More than one - third of the world's population is susceptible to active
tuberculosis, so it is unfortunate that Sutherlandia, which traditionally is taken to prevent or treat
infections, can actually cause them to develop the disease, and perhaps also cause the microbe to become a drug -
resistant «super bug.»»
· Changing nature of disease means that
infections with drug -
resistant tuberculosis will be increasingly caused by person - to - person
infection, rather than non-
resistant strains acquiring resistance.
TB kills more people than any other infectious disease, and the causative bacterium, Mycobacterium
tuberculosis, is becoming increasingly
resistant to antibiotics used to treat the
infection.
More and more people are getting
resistant to drugs that treat
infections like
tuberculosis.