«It was very satisfying to see such high
resolution electron densities by the second day of our experiment, but to then also see such strong signals from the changes in the structure was even more exciting,»
The Meiler laboratory pioneers usage of EPR spectroscopic information (Alexander, N.; et al. «De Novo High -
Resolution Protein Structure Determination from Sparse Spin - Labeling EPR Data» Structure 2008, 16, 181) and cryo
Electron Microscopy (Lindert, S.; et al. «EM-Fold: De Novo Atomic - Detail Protein Structure Determination from Medium -
Resolution Density Maps»; Structure, 2012, 20, 464).