Sentences with phrase «resolution microscopy»

Adaptive optics — a technique that originated in astronomy — has been employed in order to take light scattering into account, enabling high - resolution microscopy of mouse brain tissue through an intact skull.
This joint venture, funded by the European Research Council, EPSRC and NPL's Strategic Research Programme, is a rare blend of interdisciplinary research bringing together expertise in robotics, haptics and machine vision with synthetic and cell biology, protein design, and super - and high - resolution microscopy.
To reach that point, they first had to spend a decade standardizing, optimizing and scaling up their procedures, which involved using targeted antibodies to stain proteins and then looking for those markers inside healthy and cancerous tissue cells with high - resolution microscopy.
PA - FPs have helped to revolutionize the field of super resolution microscopy.
Prior to Joining IDRI, Matthew worked at the Institut de Biologie Integrative de la Cellule, France with Dr. Frederic Boccard applying super resolution microscopy to study the temporal and spatial localization of proteins involved in bacterial chromosome organization.
Indeed, within the world of super resolution microscopy, PA - FPs have helped create several new imaging methods, including photoactivation - localization microscopy (PALM, also FPALM)(11).
I am a postdoctoral fellow with the Garner lab employing high - resolution microscopy in live bacteria and archaea towards the understanding of the cell cycle fate.
Xiaowei Zhuang, at Harvard University, and colleagues used super resolution microscopy to follow how chromatin packing changed based on its epigenetic modifications.
Our initial device development efforts have been aimed at using the digital imaging capabilities, mobile connectivity, and computational power of a camera - enabled mobile phone to capture high - resolution microscopy images and perform subsequent image transmission or analysis.
«Hybrid approaches such as ours bring together multiple capabilities, in this case, spectroscopy and high - resolution microscopy
We have studied the mechanism of RSC - induced chromatin remodeling by using high resolution microscopy and state of the art biochemistry techniques.
Toward that end, Kavli Columbia researchers are using advanced high - resolution microscopy to detect and record processes taking place on a molecular scale.
«It is a fantastic application of atomic - resolution microscopy techniques, and it confirms that spinel formation can account for the origin of voltage fading by determining the exact location of the spinel, and how the whole structure fragments as the spinels are formed.»
At the very smallest scale, I think that improvements in high - resolution microscopy will be really central for looking at how cells work on the inside.
Because these processes are ultimately mechanical in nature, our focus is developing and applying new laser - based optical instrumentation with high - resolution microscopy imaging to understand cellular mechanics.
Professor Knight added: «Super resolution microscopy is a major step forward and we are looking forward to using this technology in a wide range of applications from stem cell behaviour to understanding arthritis or the development of nanomedicine.»
The scientists explored how the eyes are made and how well they work using high - resolution microscopy and x-ray techniques, as well as computer modeling.
While working on his Ph.D., Dr. Taraska investigated the processes of triggered exocytosis and endocytosis in neuroendocrine cells with high - resolution microscopy methods.
learn from our speakers the benefits of imaging live cells using techniques such as high resolution microscopy, superresolution microscopy, and high - content analysis
The technique combines spectroscopy, which extracts information from interactions between light and matter, with high - resolution microscopy.
The brain's inner GPS, blue LEDs and a super-high resolution microscopy technique were the discoveries that took the prestigious honors this year

Not exact matches

Using a method called two - photon microscopy, they routinely measure the activity of hundreds of neurons with single cell resolution.
Dunsby's goal was to perform light - sheet microscopy with a single objective, while maintaining good resolution.
Five years ago, using a lower - resolution form of electron microscopy in which the protein is visualized in the presence of negative stain, Whelan's team was able to detect at low resolution a structure that looked like a doughnut with three globular domains.
In near - field scanning optical microscopy, a light source or detector with dimensions less than the wavelength (λ) is placed in close proximity (λ / 50) to a sample to generate images with resolution better than the diffraction limit.
We determined a 5.8 angstrom — resolution cryo — electron microscopy and single - particle reconstruction of a ribosome stalled during translation of the tnaC leader gene.
«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the study that used cryo - electron microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.
«For developing cryo - electron microscopy for the high - resolution structure determination of biomolecules in solution,» the Royal Swedish Academy of Sciences awarded the Chemistry Prize to Jacques Dubochet of the University of Lausanne in Switzerland, Joachim Frank of Columbia University in New York City, and Richard Henderson of the MRC Laboratory of Molecular Biology in Cambridge, England.
A unique camera that can capture a detailed micron - resolution image from a distance uses a laser and techniques that borrow from holography, microscopy and «Matrix» - style bullet time.
The traditional methods used in materials science analysis, like high - powered electron microscopy and spectroscopy, do not combine chemical insights with the spatial resolution of IR imaging, the researchers said, so they can only provide average chemical measurements.
The researchers verified the structure of the nitrogenated crystal by atomic - resolution scanning tunnelling microscopy imaging and confirmed its semiconducting nature by testing it with a field effect transistor.
Additionally, they used a microscopy technique that allowed them to capture high - resolution images at different depths within the biofilms, revealing details of their three - dimensional structures.
Cryo - electron microscopy fires electrons at proteins that have been frozen in solution, providing images of such high resolution that scientists can create models down to the atomic level.
The recent study, which was produced primarily through a research partnership between the University of Arkansas, Missouri State University and the University of Antwerp in Belgium, consisted of high - resolution transmission electron microscopy combined with scanning tunneling microscopy and state - of - the - art computational molecular dynamics.
High - resolution high - contrast X-ray radiography of plant seeds combined with images taken by microscopy.
Through a combination of high - resolution cryo - electron microscopy (cryo - EM) and a unique methodology for image analysis, a team of researchers with Berkeley Lab and the University of California (UC) Berkeley has produced an atomic view of microtubules that enabled them to identify the crucial role played by a family of end - binding (EB) proteins in regulating microtubule dynamic instability.
Shim and his research team combined X-ray techniques in the synchrotron radiation facility at the U.S. Department of Energy's National Labs and atomic resolution electron microscopy at ASU to determine what causes unusual flow patterns in rocks that lie 600 miles and more deep within the Earth.
The Nobel Prize in Chemistry goes to Jacques Dubochet, Joachim Frank and Richard Henderson for developing cryo - electron microscopy for the high - resolution structure determination of biomolecules in solution.
The 2017 Nobel Prize in Chemistry was awarded jointly to Jacques Dubochet, Joachim Frank and Richard Henderson for developing cryo - electron microscopy that can determine high - resolution structures of biomolecules in solution.
Thanks to cryo - electron microscopy, «we have been able to visualise, for the first time, the high - resolution structure of the human R2TP system,» states Llorca.
The researchers were able to watch immune cells pry the virus off the nanoparticles for immune processing, using high - resolution fluorescence microscopy.
Imaging spectroscopy provides information about the local environment of the atoms, similar to the incredible resolution offered by scanning tunneling microscopy.
This achievement has been made possible by using high - resolution cryo - electron microscopy, a technique brought to the CNIO thanks to Óscar Llorca, director of the Structural Biology Programme and lead author on the paper published in Nature Communications.
The MOPID system has demonstrated both the resolution and specificity to detect malaria with both iOS - and Android - based devices and requires less user expertise than traditional microscopy, Coté says.
They then analyzed the shells with electron microscopy and other high - resolution imaging techniques.
The reported femtosecond time resolution of four - dimensional (4D) electron microscopy represents an advance of 10 orders of magnitude over that of conventional EELS methods.
Sirohi et al. present a near - atomic - resolution structure of mature Zika virus determined by cryo - electron microscopy.
By using thousands of images, they reconstructed a high - resolution cryo - electron microscopy structure of the Zika virus.
We present the 3.8 angstrom resolution structure of mature Zika virus, determined by cryo — electron microscopy (cryo - EM).
A new support for biological specimens improves the resolution that can be achieved by electron microscopy.
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