Sentences with phrase «resolution structural studies»
Because high - resolution structural studies of the human Nav1.7 channel are hindered by the molecules complexity, these researchers exploited a simpler bacterial Nav channel by fusing portions of human Nav1.7 (i.e. VSD4) onto it.
http://www.esrf.eu/ Not exact matches
«For the first time we have a room - temperature, high - resolution structure of one of the most difficult - to - study but medically important families of membrane proteins,» said Vadim Cherezov, a structural biologist at The Scripps Research Institute (TSRI) who led the research.
Even though crystallography has been successful at determining many high - resolution structures, it is challenging to use this technique to study structures which are not susceptible to crystallization or structural changes that do not naturally occur within a crystal.
Mark Chaisson, a postdoctoral fellow in Eichler's lab and lead author on the study, developed the method that made it possible to detect structural variants at the base pair resolution using this data.
In 2012, our laboratory initiated a study of AAN structural connectivity in ex vivo human brain specimens and in a living human subject - a study made possible by high resolution MRI scanners and high angular resolution diffusion imaging (HARDI) sequences developed at the Massachusetts General Hospital Athinoula A. Martinos Center for Biomedical Imaging.