Sentences with phrase «respond to other drugs»

Also, because the treatment is invasive — requiring brain surgeons to drill into the skull and deliver the therapy to the right spot in the brain — it should only be used by severely afflicted patients that don't respond to other drugs.

Genetic variation affects how people respond to other drugs as well.

Professor Josep Tabernero, a member of the scientific committee for the EORTC - NCI - AACR Symposium and head of the medical oncology department at Vall d'Hebron University Hospital and director of the Vall d'Hebron Institute of Oncology, Barcelona, Spain, commented: «These are encouraging results, which show that galeterone has significant clinical activity in men with castration - resistant prostate cancer that fails to respond to other drugs.

Not exact matches

And so drug makers and others in the health care industry have responded in force during the 2016 election — contributing heavily to both parties, including to the very politicians who are criticizing them.

The new indication puts Kymriah in direct competition with Gilead Sciences» Yescarta, which was approved by the U.S. Food and Drug Administration in October for treatment of adults with diffuse large B - cell lymphoma who have failed to respond to other treatments.

Whether the lonely person responds by losing his identity in the anonymous herd, clinging frighteningly to others, or deadens the inner ache with drugs, overeating or compulsive work, the price he pays is the increasing loneliness of superficial relationships.

The Johns Hopkins group and others have shown that so - called liquid biopsies of blood - borne tumor DNA can reveal, for example, whether a patient's cancer should respond to a specific drug.

The new drugs offer the hope of treatment to perhaps thousands of HIV patients who have stopped responding to other medications, says William Towner, medical director of the Kaiser Permanente HIV / AIDS research trials program and member of the study team, which reported its findings online today in The Lancet.

For example, changes in certain genes could indicate that his cancer was more likely to respond to a particular drug, while other mutations might predict little benefit from a specific therapy.

Though many people can survive leukemia with chemotherapy and other drugs, Porter's patients had not responded to any of the available treatments.

An oral cancer drug improves outcomes while minimizing side effects in women with gynecologic cancers who carry a BRCA mutation and whose disease is not responding to other therapies, suggests preliminary research.

In the August Cell Systems, the scientists described work designed to figure out why some patients respond to certain drugs while others don't.

Some patients respond to the drug for years, but in other patients, the treatment either fails early, or the cancer evolves resistance.

This is important because tumors are not all alike and some types of tumor cells may respond differently to a specific drug than others, Skala pointed out.

These new findings point to GABA neurons as a new, neural drug target that could help treat the other patients who don't respond to today's treatment.

«This study supports the idea that we could test ovarian cancer tumors and say they're more likely to respond to one or the other drugs,» Diamond says.

It might help guide treatment, if specific DNA affects how kids respond to certain drugs; it might alert doctors to children at risk for other cancers later in life, like breast cancer; and it might pinpoint families that could benefit from genetic counseling.

When scientists reported 2 years ago that mice with certain gut bacteria responded best to a powerful new type of cancer drug, other researchers were intrigued but cautious — mice, after all, aren't humans.

Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.

«This report may shed light on why some people respond better to anti-inflammatory drugs than others, and it suggests that a one size fits all strategy to anti-inflammatory drugs may be overly simplistic.

«We hope we can eventually use these insights to help engineer new, rational drug combinations that can more effectively treat tuberculosis and other diseases by specifically targeting the cells that are slower to respond to antibiotics.»

«What this would do is make other drugs act more potently and slow down a bacteria's natural ability to respond to a drug,» he says.

«We find that drug - sensitive tumor cells respond in similar ways to some classes of drugs and very different ways to other classes of drugs,» Sorger said.

City of Hope will be the one of the first authorized centers in the nation to provide axicabtagene ciloleucel, which the U.S. Food and Drug Administration (FDA) announced today is the first approved CAR T therapy for adult patients who have not responded to or who have relapsed after at least two other kinds of treatment.

However, escitalopram therapy is currently limited by the fact that some patients do not respond well to the drug, while others develop adverse reactions requiring discontinuation of treatment.

This research study is studying a drug TAK - 580 (MLN2480) as a possible treatment a low - grade glioma that has not responded to other treatments.

Or if used in a vaccine, they may be most effective in combination with other drugs: a few patients in the small clinical trials whose cancer relapsed after the trials responded to treatment with a checkpoint inhibitor.

Four out of the 10 colon cancer patients with the defect and 5 out of the other 7 cancer patients with the abnormality responded to the drug.

For years, researchers have come across so - called exceptional responders — people who defied all expectations by responding dramatically to a drug or treatment when others failed to do so.

This 1.5 year grant will fund Dr. Aldred's study on two drugs, ataluren and amlexanox, and perform experiments to understand why some mutations respond well to the drugs, whereas others do not.

These results reveal new risk markers in the genome that could be used to predict which children are likely to respond poorly to albuterol and other current first - line anti-asthma drugs, and to guide the development of new therapies that will be more effective and reduce the outsize burden of mortality in minority populations.

Despite adjustments for age, weight, concomitant medications, and renal or hepatic function, certain patients respond well, some experience severe adverse effects while others do not respond to the same drug therapy.

This «humanized» mouse is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies for debilitating human liver diseases and other diseases with liver involvement such as malaria.

The targeted drug brentuximab vedotin (Adcetris ®)-- a monoclonal antibody linked to a chemotherapy drug — is approved to treat Hodgkin lymphoma in patients whose disease has failed to respond to other treatment and, as of August 2015, to prevent relapse following a stem cell transplant.

But the disease did recur in the other 2 patients with stage IV melanoma, though both responded to further treatment using the immunotherapy drug pembrolizumab.

The FDA approved the drug earlier this month but wanted more detailed data on its effect on survival rates among patients who did not respond to other treatment options.

Furthermore, this will help us understand mechanistically how and why some patients may respond to the same drugs and others do not.

Unlike schizophrenia, bipolar disorder, and depression, BPD (and many other personality disorders) tend not to respond to medications, although doctors do sometimes prescribe antidepressants, atypical antipsychotic drugs, and mood stabilizers to BPD patients.

If the dog doesn't respond to cyclosporine, or the drugs proves a financial strain, there are other topical treatments available.

I take issue with lack of exercise and overweight comment, i have two german shepherds 1 is over 12 the other will be 10 in june, my eldest started to creak at 10 my vets words, the other is fine at the moment, both of these dogs have been walked for miles every day of their lives until the elder 1 started to slow down, he has been treated with all the usual drugs until they affected his stomach, i am fortunate that my vet had a vet who is qualified in acupuncture for animals, my dog has responded very well he has a very good quality of life and is happy, it is worth giving it a try or see if you dog is suitable for this, not every dog responds but it worked for mine without it he would not be here.

This drug has been chosen because your pet has not responded to other types of diuretics.

Some dogs respond well to water therapy while others have had success with a drug called Adequan, which has been used successfully in horses.

Mild cases respond to aspirin or other non-steroidal anti-inflammatory drugs such as ibuprofen or while acute cases may require the use of steroids such as prednisone or prednisolone.

Responded to incidents consisting of alcohol, illegal drug use, suicide ideation, other medical issues, flooding, key issues, and additional facility concerns

Nancy K. Young, Sydney L. Gardner, and Kimberly Dennis, Responding to Alcohol and Other Drug Problems in Child Welfare: Weaving Together Practice and Policy (Washington: CWLA Press, 1998).

A Chance to Change has responded to these changes by refining and expanding our Oklahoma City alcohol and drug addiction counseling, adding gambling addiction counseling and counseling for other addictions and disorders, and expanding treatment services to meet families» needs.

Not only is Amazon not in the space of the so - called «healthcare hubs» that CVS executives envision, but other drug store retailers are unlikely to respond in a similar way, say experts.