They then examined several aspects of the immune
response after immunization and tested how long the immunization would protect mice and rats against the plague.
Not exact matches
During the course of the
immunizations, as well as four times
after two boosters had been given, the researchers drew blood from the mice to follow their immune
responses.
After immunization with the DENV2 - E nanoparticles, mice had a specific antibody
response to serotype 2 of the dengue virus, but not the other three serotypes.
Antibody
responses were measured on serum obtained from participants at the time of each
immunization (study days 0 [baseline], 30 and 60), and 1, 4, 7 and 10 months
after the scheduled time of the last
immunization (study days 90, 180, 272 and 364).
Exploratory objectives include measuring vaccine - induced cellular immune
responses at baseline and
after immunization (results to be presented elsewhere).