Sentences with phrase «responses against inflammation»

Not exact matches

For most available T cell immunotherapies, T cells (which play a central role in defending the body against illness) are engineered to recognize and eliminate tumors, but their activity is not specifically controlled, leading to toxicity and unwanted side effects in patients as a result of inflammation or in some cases suboptimal response to treatment.

RORγt - deficient animals had exacerbated T cell responses against commensal bacteria and systemic inflammation.

Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation.

Obesity is associated with increased inflammation, which could improve the effectiveness of checkpoint blockade drugs that unleash an immune response against cancer.

Topics covered will include how the immune system and commensal microbes interact in the context of health and disease; how dendritic cells respond to infectious or inflammatory stimuli and the roles they play in the induction and polarization of adaptive immune responses against pathogens; how the innate immune pathways regulate inflammation at mucosal barrier tissue sites and how the macrophages are involved in intestinal inflammation.

The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation.

The findings, published in the Proceedings of the National Academy of Sciences, describe how myeloid differentiation factor (MyD88), a protein that plays a major role in mediating host defense response against invading pathogens, is tightly regulated to prevent uncontrolled inflammation.

Stress, anger, and fear trigger an inflammatory immune response that can rage on for weeks, flaring attacks against your thyroid and sending inflammation coursing through your body and brain.

This formula is designed to help the body maintain healthy inflammation response and protect against damage to the cardiovascular system.

Also, cats mount a much more aggressive immune response against the worms than do dogs, and the resulting inflammation is responsible for much of the damage in the feline form of this disease.