Sentences with phrase «responses following vaccination»

WRAIR and collaborators will share data related to assays designed to measure antibody responses following vaccination with ZPIV, biologic samples generated during the performance of animal studies, and biologic samples generated during the performance of early human trials assessing the safety and immunogenicity of ZPIV.

In addition, he is interested in understanding the effect that adjuvants have on the generation and maturation of antiviral antibodies, and is working to develop a number of high - throughput techniques for evaluation of complex antibody responses following vaccination in animals and humans.

Identification of optimal vaccine formulations and administration routes for the induction of CD8 + T - cell responses (SSI): The induction of suitable CD8 + T - cell responses following vaccination usually requires the use of live viral vectors.

Kim et al. suggest that moving away from empirical research to either systems analysis or hypothesis driven approaches may advance our vaccinology understanding.5 Interrogation of peripheral blood responses following vaccination, termed «systems vaccinology», has led to the identification of immune signatures and pathways that are correlated to immune responses.

Feral cats appeared to have an excellent immune response following vaccination at the time of neutering.

Recent studies have alleviated these concerns by demonstrating that cats do develop a strong immune response following vaccination at the time of spay / neuter.

Not exact matches

Breastfeeding consistently reduced behavioural responses of cry duration and composite pain scores during and following vaccinations.

Researchers used the immune suppressing drug rapamycin to shift the immune response following flu vaccination to favor production of antibodies that broadly target flu viruses.

They found substantial differences following influenza vaccination in the production of immune - modulators that determine the type of T - cell response and in the proliferation and production of antibodies by B cells.

Further analysis showed that the improved antibody response following AMA1 - RON2 vaccination was due to an increased proportion of antibodies aimed directly at the AMA1 - RON2 junction, which made them better at inhibiting parasite invasion.

In contrast, similar ASC responses were not detected following the second dose of vaccination.

The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

(iii) Test various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

The development of anti-galectin 3 polyclonal responses in pancreatic cancer patients after vaccination with GVAX (2) or prostate cancer patients following Sipuleucel - T (3) has been associated to prolonged survival, thus providing an supportive rationale for targeting galectin 3.

Working with Dr. Weiskopf, we established a model of human dengue disease using HLA transgenic mouse strains, and characterized human dengue - specific CD8 + and CD4 + T - cell responses in natural infection as well as following vaccination.

The latter work addresses questions including whether infection with different serotypes is associated with distinct types of T cell responses, whether any HLA alleles are associated with pathogenesis or protection, and whether vaccination with a formulation in clinical trials is associated with T cell responses similar to those following infection that might serve as correlates of protection.

Broad heparin - binding haemagglutinin - specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination.

Post-Infection Cellular Immune Responses in Recipients Following ALVAC - HIV ® + AIDSVAX ® B / E Prime - boost Vaccination in the Thai Phase III Trial

Vaccination can provide an immune response that's comparable in length to that following a pure an infection.

Conclusions and Clinical Relevance — Results indicated that dogs with out - of - date vaccination status were not inferior in their antibody response following booster rabies vaccination, compared with dogs with current vaccination status.

This is because the second vaccination will produce a much greater (logarithmically greater) response if it is following a vaccine given 2 - 4 weeks prior.