Sentences with phrase «responses in lung»

Clinical responses in lung cancer patients have been impressive, with responses in patients with advance disease whose cancers did not respond to other treatment approaches.

«I've never seen such a dramatic protective response in the lung before.»

DENVER — With the flip of a cellular switch, reactive molecules in air pollution can turn immune responses in the lungs topsy - turvy.

However, the treatment did significantly reduce the severity of the asthma by counteracting one aspect of the specific immune response in the lungs.

This included detailed comparisons between immune T cell responses in the lungs, spleen and blood.

Yes, you can rub it on their chest and neck, but a surprisingly soothing way to use the baby chest rub is to massage it into your little one's feet, focusing from the ball of the foot to the toes (reflexology says this is the point to focus on to induce a healing response in the lungs and sinuses).

I use it for a soothing foot massage, rubbing onto my little one's feet, focusing from the ball of the foot to the toes (reflexology says this is the point to focus on to induce a healing response in the lungs and sinuses).

Short - and long - term stress is known to suppress the immune response in the lungs, throat, urinary tract and intestines.

HW - associated inflammatory mediators that induce immune responses in the lungs and kidneys (immune complex glomerulonephritis) cause vasoconstriction and possibly bronchoconstriction.

Inhaled Glutathione for Lung Inflammation, Pneumonia, Emphysema Glutathione reduces oxidative stress, decreases inflammation, and modulates T cell responses in lungs.

Corticosteroids help to control the inflammatory response in the lungs.

Not exact matches

In addition, the buildup of mucous in the lungs, as a result of this immune response to infection, induces coughing as a reflex to try to clear the airwayIn addition, the buildup of mucous in the lungs, as a result of this immune response to infection, induces coughing as a reflex to try to clear the airwayin the lungs, as a result of this immune response to infection, induces coughing as a reflex to try to clear the airways.

Oliver added that the executive was «on the same side as black lung» and bashed his response to a 2007 mine accident in Utah that killed nine people.

Related Articles: Merck's Keytruda held back by docs who don't want to wait for diagnostics Bristol's Opdivo - Yervoy combo ups response rates in first - line lung cancer patients Roche's Tecentriq bursts onto immuno - oncology scene, with Merck and BMS in its sights Bristol - Myers» new Opdivo ad touts biomarker advantage over Merck's Keytruda Merck's Keytruda lines up its survival data for stepped - up battle with BMS» Opdivo

The biotech specialist said that its updated phase 2 data in a study of its poziotinib candidate treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form of the disease.

Examples I personally can document: a plague of deadly bacteria in the newborn nursery killing 3 previously healthy newborns, exploding the fetal lungs with too forceful dose of oxygen after birth by inexperienced doctor, crushing the skull during forceps extraction, overdose of adrenalin to newborn by a nurse, slow paging or slow response to call to resuscitate newborn, exploding the uterus (uterine rupture) and / or placental abruption as a result of high IV dose of oxytocin in labor in a low risk women.

The ability to counteract inflammation in the lungs by utilising the combined anti-inflammatory and reparative properties of MSCs could potentially reduce the inflammatory response in individuals with chronic lung disease whilst also restoring lung function in these patients.

Highly pathogenic (dangerous) influenza strains elicit a strong immune response which can lead to uncontrolled inflammation in the lung and potentially fatal lung injury.

«We were fascinated to find that, without the influence of Myb, Treg cells would allow the immune response to spin out of control, resulting in severe inflammation pretty much everywhere — whether in the lungs, liver, intestine or skin,» she said.

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.

Immunotherapy with a live bacterium combined with chemotherapy demonstrated more than 90 % disease control and 59 % response rate in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.1

Originally, researchers thought Th2 response had evolved to promote tissue repair; however, in the context of lung virus infections, Th2 cells appear to contribute to the overactive immune responses that endanger patients.

The study, published in the Journal of General Internal Medicine, analyzed biannual responses from 13,897 participants in the University of Michigan's Health and Retirement Study who were 54 or older and had at least one of the following chronic conditions: hypertension, diabetes, cancer, lung disease, heart disease or stroke.

Research has already shown that immune response provided by nasal mucous membranes is compromised in cigarette smokers, which causes them to be more susceptible to the outcomes of a viral infection, said Ilona Jaspers, deputy director of the Center for Environmental Medicine Asthma and Lung Biology at the University of North Carolina at Chapel Hill, but her new research revealed even more immune suppression effects in e-cigarette users than in smokers of traditional cigarettes.

«We have shown for the first time that the immune response, especially in the aged lung, plays an essential role in the pathogenesis of the disease.

In this study, immune cell infiltration of the lungs increased, and Th2 responses became more prominent.

Their finding — that the presence of high levels of NF - κB in lung cancer tumors can act as a suppressor — provides new insight into how tumor pathways regulate the anti-tumor response.

Once influenza spreads deep into the lungs, the body's own immune response can prove harmful, resulting in severe damage to the alveolar air sacs.

In those cases, learning how to dampen the lungs» immune response could help, Yipp says.

But, he notes, «with all infections, part of the concern is that the inflammatory response can become too exuberant, which leads to tissue damage, as in septic shock,» and lung failure.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

All of these findings were supplemented with several other experiments that were designed to learn how CHI3L1 interacts with other cells involved in the tissue repair response in both human and mouse lungs.

According to Harkema, the DHA could be changing the way these cells, also known as macrophages, react to the silica in the lungs and somehow alter the immune system's response.

Principal Investigator John Morris, MD, clinical co-leader of the Molecular Therapeutics and Diagnosis Program for the CCC, co-leader of the UC Cancer Institute's Comprehensive Lung Cancer Program, professor in the division of hematology oncology at the UC College of Medicine and UC Health medical oncologist, says a number of antitumor vaccines have shown promise for causing immune responses against tumor antigens to improve patient outcomes.

In asthma this aberrant immune response leads to immune cells infiltrating the lungs, where they cause inflammation that affects lung function and leads to difficulties in breathinIn asthma this aberrant immune response leads to immune cells infiltrating the lungs, where they cause inflammation that affects lung function and leads to difficulties in breathinin breathing.

In additional experiments, the NYU team showed that the TB - transporting dendritic cells had to first pass through the lungs — as would be expected in the natural course of the disease that is passed by someone breathing in infected droplets — before heading to the lymph nodes to elicit a strong immune responsIn additional experiments, the NYU team showed that the TB - transporting dendritic cells had to first pass through the lungs — as would be expected in the natural course of the disease that is passed by someone breathing in infected droplets — before heading to the lymph nodes to elicit a strong immune responsin the natural course of the disease that is passed by someone breathing in infected droplets — before heading to the lymph nodes to elicit a strong immune responsin infected droplets — before heading to the lymph nodes to elicit a strong immune response.

To test the aptamer's mettle in animals, Smith and his colleagues provoked a strong immune response in rat lungs.

Yet, to our surprise, this response significantly differs from the reaction to direct exposure of house dust mites in the lungs without prior skin inflammation.

In a cross-sectional study, these researchers evaluated the responses to a socioeconomic questionnaire filled out by more than 530 patients who had undergone lung transplantation in 2009 or 201In a cross-sectional study, these researchers evaluated the responses to a socioeconomic questionnaire filled out by more than 530 patients who had undergone lung transplantation in 2009 or 201in 2009 or 2010.

But new research at Washington University School of Medicine in St. Louis suggests that broadly dampening the immune response, long considered crucial to transplant success, may encourage lung transplant rejection.

By comparing gene expression in the lungs of ducks infected with either highly or weakly pathogenic avian influenza H5N1 viruses, the team identified genes whose expression patterns were altered in response to avian influenza viruses.

Transplant recipients who receive a kidney, heart, or lung often develop an immune response to the foreign tissue in the form of antibodies referred as donor - specific HLA antibodies.

The scientists hypothesized that the fish's air - filled lungs might be responsible, because the air inside them buzzes and rattles in response to a propagating pressure wave.

He says that any animal with air - filled lungs that vibrate in response to pressure waves «will hear pressure in water whether it wants to or not.»

«Lungs started to appear in fish underwater when they evolved air breathing in response to low oxygen levels in water 350 to 400 million years ago,» says study author Peter Madsen, a biologist at Aarhus University in Denmark.

The immune response that occurs in patients with severe asthma is markedly different than what occurs in milder forms of the lung condition, according to researchers from the University of Pittsburgh School of Medicine.

The stem cells that proliferate the most in response to damage caused by cigarette smoke repair their DNA using a process prone to errors, setting the stage for lung cancer, according to a study publishing January 26, 2017 in the open - access journal PLOS Biology by Marie - Liesse Asselin - Labat and her team of the Walter and Eliza hall Institute of Medical Research, Australia.

To explore these issues, the authors isolated both types of cells from the lungs of heavy smokers and compared the activity of their genes, their rates of cell division, and their ability to repair their DNA in response to damage.

In collaboration with researchers in the Netherlands at University Hospital in Groningen and Rehab Beatrixoord in Haren, Howard found that a mutation in IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmIn collaboration with researchers in the Netherlands at University Hospital in Groningen and Rehab Beatrixoord in Haren, Howard found that a mutation in IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmin the Netherlands at University Hospital in Groningen and Rehab Beatrixoord in Haren, Howard found that a mutation in IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmin Groningen and Rehab Beatrixoord in Haren, Howard found that a mutation in IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmin Haren, Howard found that a mutation in IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmin IL13 was associated with extreme contraction of the lungs in response to an inhaled chemical, a symptom of asthmin response to an inhaled chemical, a symptom of asthma.

This is due to water retentions in the lung tissues (oedemas) and to a massive inflammatory response that, at the end, destroys lung tissues and hinders gas exchange.