Sentences with phrase «restored by gene therapy»

In previous work, Dr. Ryosei Minoda, head of the Department of Otolaryngology at Kumamoto General Hospital, reported that hearing loss was restored by gene therapy to the inner ear of Connexin 30 deficient fetal mice.

Not exact matches

Since patients (and mice) with Usher 1c also have balance problems caused by hair - cell damage in the vestibular organs, the researchers also tested whether gene therapy restored balance.

Indeed, exposure of the protein produced by the nanoparticle - based gene therapy to the gut mucosa prevents inhibitor development and restores clotting - factor activity in mouse models of both haemophilia A and B. «This approach really could hold big benefit for patients,» says Jörg Schüttrumpf, a transfusion - medicine specialist who led one of the studies performed at the German Red Cross Blood Donor Service in Frankfurt.

The findings by Dr. Pang and his colleagues indicated that gene therapy might be able to stop cone degeneration during early Leber congenital amaurosis and restore the function and morphology of the cones still surviving in later stages of human LCA.

A team of Chinese and American researchers led by Dr. Ji - jing Pang of the Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, PR China, and including Jackson Laboratory scientist Bo Chang, M.D., used gene therapy to restore cone function in the retinas of the B6 (A)- Rpe65rd12 / J (005379) mouse, a model of Leber congenital amaurosis — even if the disease has progressed for three months (Li et al. 2011; Pang et al. 2005).

Yet, their efforts to rescue cone function by gene therapy in mid-course LCA stages failed: when applied to 35 - day old Rpe65 - deficient mice, gene therapy restores rod function only (Pang et al. 2010).

By targeting these cells with gene therapy and virtual reality stimulation, we hope to rescue them and prevent vision loss, perhaps even restore vision.