Sentences with phrase «result in a zinc»

Each ZFP was then fused to a modified FokI cleavage domain, active preferentially as a dimer to reduce nonspecific DNA cleavage, resulting in zinc - finger nucleases (ZFNs)[25].

Folate is less liable to overdose and result in a zinc deficiency.

Not exact matches

Shares in Rox Resources more than doubled today on the back of a strong zinc and lead drilling result at a project in the Northern Territory, while Dacian Gold was up 7 per cent following results in Western Australia.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

POSITIVE early drilling results from its Mt Garnet zinc project in North Queensland has indicated likely ore body extensions at depth for recently listed junior Kagara Zinc Limizinc project in North Queensland has indicated likely ore body extensions at depth for recently listed junior Kagara Zinc LimiZinc Limited.

In the base metals complex, only nickel and tin traded higher for the quarter.4 A slow start to Chinese restocking coming out of the Chinese New Year holiday weighed on prices for copper and aluminum, both of which saw their worst quarterly results in years, while zinc and lead prices also declined.4 The London Metal Exchange (LME) Index, which tracks the three - month futures prices of all six metals, fell 6.3 %.4 LME copper -LRB--7.4 %, to US$ 6,714 per mt) and other industrial metals erased some of their 2017 gains, falling alongside a sharply decelerating expansion in China's manufacturing activity — sparking demand concerns and greater caution among hedge funds and other speculators who cut their net long positions in the metal.4 Outside the LME, US steel was buoyed by trade policy changeIn the base metals complex, only nickel and tin traded higher for the quarter.4 A slow start to Chinese restocking coming out of the Chinese New Year holiday weighed on prices for copper and aluminum, both of which saw their worst quarterly results in years, while zinc and lead prices also declined.4 The London Metal Exchange (LME) Index, which tracks the three - month futures prices of all six metals, fell 6.3 %.4 LME copper -LRB--7.4 %, to US$ 6,714 per mt) and other industrial metals erased some of their 2017 gains, falling alongside a sharply decelerating expansion in China's manufacturing activity — sparking demand concerns and greater caution among hedge funds and other speculators who cut their net long positions in the metal.4 Outside the LME, US steel was buoyed by trade policy changein years, while zinc and lead prices also declined.4 The London Metal Exchange (LME) Index, which tracks the three - month futures prices of all six metals, fell 6.3 %.4 LME copper -LRB--7.4 %, to US$ 6,714 per mt) and other industrial metals erased some of their 2017 gains, falling alongside a sharply decelerating expansion in China's manufacturing activity — sparking demand concerns and greater caution among hedge funds and other speculators who cut their net long positions in the metal.4 Outside the LME, US steel was buoyed by trade policy changein China's manufacturing activity — sparking demand concerns and greater caution among hedge funds and other speculators who cut their net long positions in the metal.4 Outside the LME, US steel was buoyed by trade policy changein the metal.4 Outside the LME, US steel was buoyed by trade policy changes.

Zinc production, meanwhile, decreased by 7 % year - on - year to 242 700 t for the first quarter, mainly as a result of the disposal of the Rosh Pinah mine, in Namibia, and the Perkoa mine, in Burkina Faso, to Canadian miner Trevali Mining in August last year.

The drop was somewhat surprising given that Teck more than quadrupled its adjusted earnings during the quarter, riding strong operating results for its steelmaking coal segment as well as record zinc production at its Antamina mine in Peru.

Tinka Resources Ltd. [TK - TSXV; TKRFF - OTC] reported results of five additional drill holes from its 100 % - owned Ayawilca zinc project in central Peru.

Arizona Mining Inc. [AZ - TSX] reported the results of three exploration drill holes from its current program on the Taylor zinc - lead - silver sulfide deposit located on its 100 % - owned Hermosa Project in Santa... Read more»

Studies point to phytic acid reduction that results in greater bioavailabilty of nutrients like iron, zinc and magnesium.

According to a spokesperson for the Administration, «All or almost all of the sunscreens available in Australia that have zinc oxide as their only active ingredient have a claimed SPF of 30 + (which means that their SPF test result was 31 or higher) and they typically contain between 15 % and 25 % zinc oxide.»

After six months, the addition of stabilized oats resulted in an increased intake of vitamin B1 and magnesium, while the unkilned oats increased intakes of magnesium and zinc.

Deficiency of Zinc results in growth failure and sexual infantilism in adolescents.

In a new study, Scripps Institution of Oceanography at the University of California San Diego Professor James Day and colleagues examined the chemical composition of zinc and other volatile elements contained in the green - colored glass, called trinitite, which were radioactive materials formed under the extreme temperatures that resulted from the 1945 plutonium bomb explosioIn a new study, Scripps Institution of Oceanography at the University of California San Diego Professor James Day and colleagues examined the chemical composition of zinc and other volatile elements contained in the green - colored glass, called trinitite, which were radioactive materials formed under the extreme temperatures that resulted from the 1945 plutonium bomb explosioin the green - colored glass, called trinitite, which were radioactive materials formed under the extreme temperatures that resulted from the 1945 plutonium bomb explosion.

The real reason, however, may be much simpler: the accumulation of undigested food inside the gastrointestinal tract due to zinc deficiency results in feeling less hungry,» says Brugger.

«However, while these encouraging results in mice mean that the zinc finger looks like a good candidate to take forward to human trials, we still need to do a lot of work first to answer important questions around the safety of the intervention, whether repeat treatments are effective, whether there might be longer - term side effects, and whether we can extend and increase the benefits beyond six months.

«But zinc deficiency during sepsis appears to cause a catastrophic malfunctioning of the system, resulting in a magnified and prolonged inflammatory response.»

That knowledge unveils the path to breeding plants with enhanced activity of this particular transport system resulting in more zinc rich seeds.»

«We found that they are a result of zinc atoms that were incorrectly positioned in the crystal lattice,» says Zheng.

Diaz noted that this research and follow - up studies may result in a recommendation for women intending to get pregnant to make a special effort to eat foods containing zinc in the weeks prior to ovulation, or even to take zinc supplements.

For DNA cleavage to occur, two zinc finger proteins must bind, each to specific, adjoining sequences in the CCR5 gene, leading to FokI dimerization and subsequent DNA cleavage resulting in a double strand break [24]--[26].

«By further examining zinc metallochaperones on other p53 mutants that are similarly structured, we have an opportunity to increase the potential pool of patients that could theoretically benefit from zinc metallochaperones resulting in broad activity against all cancer types.

An insufficiency of zinc can result in the development of cancers as well as other diseases, and this is why it's important to have a well balanced diet.

In this study on zinc and hormones, it was found that the addition of zinc to the diet of zinc - deficient elderly men, who were otherwise normal, resulted in a statistically significant increase in serum testosterone levels over the course of six monthIn this study on zinc and hormones, it was found that the addition of zinc to the diet of zinc - deficient elderly men, who were otherwise normal, resulted in a statistically significant increase in serum testosterone levels over the course of six monthin a statistically significant increase in serum testosterone levels over the course of six monthin serum testosterone levels over the course of six months.

Regular intakes of selenium combined with zinc could help with protecting against glaucoma, which can ultimately result in damage to the optic nerve and blindness.

Studies vary tremendously on toxicity levels with some reporting as low as 75 mg, some saying 500 - 1,000 mg, and one reporting 10, ooomg or more in one single dose resulting in nausea, vomiting and diarrhea from zinc.

On the flip side, numerous studies show that a zinc deficiency will result in a dramatic decrease of testosterone levels.Experts agree that diet is better than sup - plementation when it comes to zinc.

Avoid using phytate or phytic acid (also known as IP6) to prevent iron absorption and chelate iron out of your body, however, as this can easily result in other mineral deficiencies, such as zinc deficiency.

The end result for acne is 1) improved absorption of vital nutrients like zinc, 2) prevention of leaky gut syndrome, 3) resistance to acne caused by slow digesting carbohydrates like FODMAPs, and 4) a reduction in stress, because good gut bacteria manufactures up to 95 % of your body's serotonin.

While use of these products as directed (0.5 — 1.5 g / day) is not of concern, chronic, excessive use can lead to zinc toxicity, resulting in copper deficiency and neurologic disease.

It's best to get zinc from your food, however, as too much in supplements (more than 100 mg a day) can result in side effects.

Results show that spirulina mixed with zinc twice daily for 16 weeks caused a substantial improvement in symptoms.

In addition, results from a pooled analysis of randomized controlled trials of zinc supplementation in developing countries suggest that zinc helps reduce the duration and severity of diarrhea in zinc - deficient or otherwise malnourished children [62In addition, results from a pooled analysis of randomized controlled trials of zinc supplementation in developing countries suggest that zinc helps reduce the duration and severity of diarrhea in zinc - deficient or otherwise malnourished children [62in developing countries suggest that zinc helps reduce the duration and severity of diarrhea in zinc - deficient or otherwise malnourished children [62in zinc - deficient or otherwise malnourished children [62].

The main single mineral levels that I'm most interested in is my Magnesium, Zinc, Copper for the main reasons that I had been supplementing with Zinc (prescribed by my Kinesiologist) for 2 years up until November 2016 when my Kinesiologist said that I no longer needed it anymore so I'm keen to see what my results show.

The result is toxic accumulation of copper in tissues and critical depletion of zinc through excretion.

Phytic acid in soy foods results in reduced bioavailabilty of iron and zinc which are required for the health and development of the brain and nervous system.

Kerrie - I decided to bite the bullet, and ordered a really expensive advanced functional medicine nutrient analysis test for myself, that uses a unique technology to pick up nutrient deficiencies that traditional tests miss (the Spectracell test that I discuss in my book, Hashimoto's The Root Cause) I had already done a lot of research on the nutrients that were causing some of my symptoms, including glutamine, zinc and the B vitamins so many of the results were not surprising, except for one: I was deficient in Thiamine!

Most people have a zinc deficiency resulting in low testosterone in the body.

Inadequate amount of zinc in our body results to loss of appetite and malfunction of the immune system.

Zinc deficiency in the mother during the last trimester of pregnancy has resulted in behavior disorders in the offspring.

Zinc deficiency can result in teratogenic effects in animal models.

Studies report that men with BPH who take 45 mg of zinc daily results in improved symptoms of frequent urination and / or difficult urination, and an actual shrinkage of a swollen prostate.

It appears that a zinc deficiency may result in decreased neurologic functioning, activity, which therefore would interfere with cognitive function.

In animals and humans, zinc deficiency results in rapid and marked atrophy of the thymus, impaired cell - mediated cutaneous sensitivity and lymphopeniIn animals and humans, zinc deficiency results in rapid and marked atrophy of the thymus, impaired cell - mediated cutaneous sensitivity and lymphopeniin rapid and marked atrophy of the thymus, impaired cell - mediated cutaneous sensitivity and lymphopenia.

It should also be noted that an excessive intake of zinc (300 mg / d, 20 times the recommended daily allowance) results in significant immune impairment in healthy adult men (Chandra 1985).

Use a leave - in conditioner that contains zinc oxide for best results, and really let your locks soak it up and re-hydrate.

For the ultimate result of the bankruptcy, you can read this article in the Wall Street Journal: Zinc Producer Horsehead Cleared to Exit Bankruptcy.

Particularly, the nutritional deficiencies include choline, vitamin D, zinc and vitamin E, «which could result in significant health problems such as immune dysfunction, accumulation of fat in the liver and musculoskeletal abnormalities,» PawNation reports.

If ingested, some metals (especially zinc and lead) can result in serious poisoning.