One
result of the new environment could be some players attempting a «brisk and desperate grab at immediate liquidity».
Though neuroplasticity is not a new concept, science continues to confirm the brain's ability to change as
a result of new environments, behaviors, and emotions.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial
results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for
new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic
environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable
results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit
new drug applications for
new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for
new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
«This issuance reflects OnDeck's most successful securitization issuance to date, with strong investor interest
resulting in broad participation by existing and
new institutional investors, expected improvement in credit ratings, and a significant reduction in cost
of funds despite a rising interest rate
environment, and is a testament to the strength
of OnDeck's business model.»
Given the absence
of a public trading market
of our common stock, and in accordance with the American Institute
of Certified Public Accountants Accounting and Valuation Guide, Valuation
of Privately - Held Company Equity Securities Issued as Compensation, our board
of directors exercised reasonable judgment and considered numerous and subjective factors to determine the best estimate
of fair value
of our common stock, including independent third - party valuations
of our common stock; the prices at which we sold shares
of our convertible preferred stock to outside investors in arms - length transactions; the rights, preferences, and privileges
of our convertible preferred stock relative to those
of our common stock; our operating
results, financial position, and capital resources; current business conditions and projections; the lack
of marketability
of our common stock; the hiring
of key personnel and the experience
of our management; the introduction
of new products; our stage
of development and material risks related to our business; the fact that the option grants involve illiquid securities in a private company; the likelihood
of achieving a liquidity event, such as an initial public offering or a sale
of our company given the prevailing market conditions and the nature and history
of our business; industry trends and competitive
environment; trends in consumer spending, including consumer confidence; and overall economic indicators, including gross domestic product, employment, inflation and interest rates, and the general economic outlook.
«The net
result of the Liberals» carbon trust shell game is that year after year money gets drained from classrooms and emergency rooms without any
resulting efficiency gains while big polluters like Encana get a free ride funded by our healthcare and education systems,» said
New Democrat
environment critic Rob Fleming.
The concept
of ecosystem and
environment captures the unifying, inter-relativity
of local physical phenomena even when they don't
result in
new chemical or biological unities.
What is interesting is that sales
of organic products have increased markedly as a
result of recent food scares88, suggesting that
new consumers are concerned about the product itself as well as, or perhaps rather than, the
environment in which it is produced.
All
of these things will help to reduce your baby's stress as he acclimates to his
new environment, and a less stressed baby tends to
result in a less stressed mommy.
These
results contribute to the evidence that significant improvement in the nutrition
environments in schools is associated with the enactment and implementation
of the
new US Department
of Agriculture meal standards, with corresponding improvement
of student selection
of nutritious foods, without negatively affecting meal participation.
«From leading the fight to get PCBs out
of the classroom, to sponsoring the Council Resolution to prohibit fracking in
New York State, to fighting to protect children from the deadly effects
of lead both here in NYC and in the Dominican Republic, Robert Jackson has been a leader willing to take bold actions on the
environment and get
results.
ERIE COUNTY, NY — The Erie County Department
of Environment & Planning («DEP»), in partnership with the Lake Erie Watershed Protection Alliance («LEWPA») and Buffalo Niagara Riverkeeper, has announced plans to begin Phase II
of the Regional Niagara River / Lake Erie Watershed Management Plan following their successful application for
New York State Consolidated Funding, which
resulted in an award
of $ 507,830 from the NYS Department
of State to pursue the Plan.
The risk
of catastrophic danger to the
environment, the health
of New York State residents and adverse economic impacts that
result from hydraulic fracturing far outweigh the potential for job creation and promotion
of a natural gas alternative to oil.
The
new results from SPHERE, along with data from other telescopes such as ALMA, are revolutionising astronomers» understanding
of the
environments around young stars and the complex mechanisms
of planetary formation.
In addition to providing
new insights into how genes and the
environment interact, the
results may have early implications for clinical management
of CD.
In previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the
environment resulted in the growth
of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networks.
The
results show that changes in the
environment strongly influence extinctions but surprisingly not the origination
of new diversity.
Using the
results of their research, they were able to build upon Ahuja's model and propose a
new model they hope will «re-energize the dialogue regarding creating a more diversified IT work
environment,» according to the study.
A set
of crucial immunity genes do not turn on in a simulated microgravity
environment, suggest the
results of a
new study.
Recent modeling along with previously published
results from NASA's MESSENGER spacecraft — short for Mercury Surface, Space
Environment, Geochemistry and Ranging, a mission that observed Mercury from 2011 to 2015 — has shed
new light on how certain types
of comets influence the lopsided bombardment
of Mercury's surface by tiny dust particles called micrometeoroids.
The Canadian government's Innovation Strategy urges
new measures to strengthen our R&D capacity and to create a more welcoming
environment for industry receptors, companies that are willing to gamble on bringing the
results of R&D to market.
«Increasingly we are learning that health disparities in cardiovascular disease and diabetes tend to
result from
environments that expose residents to social or nutritive stress,» says Richard Scribner, MD, MPH, Professor
of Epidemiology at LSU Health
New Orleans School
of Public Health.
Walking along the beaches
of New England, it is easy to spot large amounts
of a fine red seaweed clogging the coastline, the
result of sweeping changes in the marine
environment occurring beneath the water.
The
results of the study also suggest that life can be sustained even in remote, cold, nutrient poor
environments, offering a
new perspective on whether the frozen planets
of the universe could support microorganisms.
«With this
new information describing the diversity
of arsenic - reducing microorganisms, we are further exploring relationships between these organisms and their biogeochemical
environments that
result in arsenic contamination
of groundwater.»
«As a
result, traits that might have been beneficial in adapting to challenging
new non-African
environments could easily be detrimental over the course
of a long life without significant risk
of infectious disease or starvation.»
A meeting was called
of citizen groups and individuals in early 2002 as a
result of shared problems and concerns regarding the approval
of several solid waste and hazardous waste landfills by the
New Mexico
Environment Department (NMED) in 2001 and 2002.
When marine biology and microbiology come together with bionics, this can
result in unimagined discoveries and thus the development
of new methods that humans can implement for their own benefit and for the protection
of the
environment.
The
new results indicate that the very sedate, elderly
environments of globular clusters house these exotic objects, quite unlike the violent cores
of some galaxies.
Results: Proteomics experts at Pacific Northwest National Laboratory contributed to a study published in Science magazine centered on discovery
of new bacteria and the metabolic roles, such as carbon cycling,
of bacteria in the
environment.
It might be the last thing you want to do, but not taking medication, in combination with the stress
of a
new life and a
new environment, could
result in an emergency room visit or worse.
Area X is a foreboding, inhospitable land where the laws
of physics and nature have turned in on themselves as the
environment mutates with
new and fascinating
results.
I forged
new creative and business relationships in this
environment and, as a
result, it opened my eyes to a whole
new way
of getting movies made.
As a
result, instructors who are trying to apply this theory in their classes are encouraged to create an
environment of full immersion, wherein students must be able to learn skills, as well as
new ideas and behaviors that are taught in the context in which they will be used at a later time.
Given that these students had no clear incentives for participation (e.g., academic credit) and were
new to this type
of peer instruction, our
results suggest that there is considerable potential for productive clicker use in the middle school
environment.
OAKLAND, CA — The Black Teacher Project, a national organization with programming in Oakland, CA, San Francisco, CA and
New York, NY, is excited to announce the development of Institutional Transformation, a new project that will result in more positive work environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for studen
New York, NY, is excited to announce the development
of Institutional Transformation, a
new project that will result in more positive work environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for studen
new project that will
result in more positive work
environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for students.
«As a
result of the
new duty, I expect to see schools setting up careers events, assemblies and options evenings so that providers can talk to pupils about what they offer and what it is like to learn in a different
environment,» she wrote.
Combatants on both sides
of that fight could claim a measure
of validation from the
new research: Advocates
of school choice who argue that it isn't fair to judge voucher programs based on test
results from a student's first year in private school, given that it takes children time to adjust to a
new environment, and critics who say vouchers drain funds from public schools without improving student achievement.
These
results stem from a range
of measures now in place at the school, including an intense focus on creating a nurturing
environment inside and outside
of the classroom, along with
new scheduling and staffing arrangements and a unique partnership with the University
of California, San Diego.
The
results of the NHPS School Learning
Environment Survey (also known as the School Climate Survey) are being presented in a
new format this year using a web - based system that allows users to view reports broken down by school, stakeholder and question.
First - year teachers often feel underprepared when they first enter the classroom, and are less likely than more experienced teachers to report being well prepared to implement state or district curriculum.45 As a
result, nearly one in seven
new teachers leaves the classroom before completing their third year, with most citing classroom management, the burden
of curriculum freedom, and unsupportive school
environments as their greatest stressors.46 Too often, teachers begin their careers in a sink - or - swim situation, with little to no formal induction or support system and inadequate professional learning.47 By providing
new teachers with evidence - based professional learning — including through comprehensive, high - quality induction programs — schools and districts can create a more supportive pathway to success in the classroom.
The online Professional Learning
Environment (PLE) instills a deeper understanding
of program strategies through collaboration with other educators, delivering better classroom
results while inspiring a
new generation
of students.
OAKLAND, CA — The Black Teacher Project, a national organization with programming in Oakland, CA, San Francisco, CA and
New York, NY, is excited to announce the development of Institutional Transformation, a new project that will result in more positive work environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for... Continue reading Black Teacher Project to Improve Student Outcomes by Facilitating Supportive Workplaces for Black Teacher
New York, NY, is excited to announce the development
of Institutional Transformation, a
new project that will result in more positive work environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for... Continue reading Black Teacher Project to Improve Student Outcomes by Facilitating Supportive Workplaces for Black Teacher
new project that will
result in more positive work
environments for Black teachers, improved leadership capacity, and ultimately improved learning outcomes for... Continue reading Black Teacher Project to Improve Student Outcomes by Facilitating Supportive Workplaces for Black Teachers →
As a
result of the State Board
of Education's action, the
New Haven Board
of Education approved Agreement 649 - 14 with Clemons» Connecticut Center for Arts and Technology (ConnCAT) to «provide after - school programming, family and community engagement programs and school
environment transformation at Lincoln - Bassett School from July 1, 2014 to June 30, 2015.
Teachers with three or fewer years
of teaching experience also report feeling less prepared to maintain order and discipline in the classroom or to implement state or district curricula.52 As a
result, 10 percent
of new teachers leave the classroom after their first year — with most citing classroom management, a lack
of time and resources for lesson planning, and unsupportive school
environments as their greatest stressors.53
Actual
results may differ materially from those expected because
of various known and unknown risks and uncertainties, including, but not limited to, the continuing effects
of the U.S. recession and global credit
environment, other changes in general economic and industry conditions, the award or loss
of significant client assignments, timing
of contracts, recruiting and
new business solicitation efforts, currency fluctuations, and other factors affecting the financial health
of our clients.
The 458 Italia features an innovative driving
environment with a
new kind
of steering wheel and dashboard that is the direct
result of racing practice.
In reality, hunter - gatherers were unbelievably skilled (a point also made by Jared Diamond in his classic Guns, Germs and Steel, in which, if I recollect correctly, he makes a compelling case that as a
result of natural selection and their
environment, the indigenous people
of Papua
New Guinea are, on average, more intelligent than so called «first world *» inhabitants).
-- quoted in
New York Magazine «The
result [
of the 2008 financial crisis] will be a «Darwinian»
environment (only the fittest will survive), and the retail species will have to adapt or face extinction.
This open access book presents the most current research
results and knowledge from five multidisciplinary themes: Vulnerability
of Arctic
Environments, Vulnerability
of Arctic Societies, Local and Traditional Knowledge, Building Long - term Human Capacity,
New Markets for the Arctic, including tourism and safety.