Sentences with phrase «resulting immune activation»

«This suggests lowering viral replicative capacity and the resulting immune activation might have benefits, in terms of morbidity and mortality, for individuals whether they remain treatment naïve or go on antiretroviral therapy.

Not exact matches

«The results are novel, as this sensitive and comprehensive testing has revealed how prenatal and early postnatal immune activation may regulate core behavioral signs associated with ASD and certain other developmental disorders through changes in signal flow between different structural components of behavior - driving neural circuits,» said Bolshakov.
The study results builds on prior investigations by the research team which demonstrated that activation of the PI3K pathway by PTEN tumor loss created a «microenvironment» allowing tumors to evade immune suppression.
«While transient disruption of this pathway may have therapeutic benefit because it temporarily «revs up» the immune response, permanent loss of PD - 1 signals seems to result in a «flame out» where T cells can't sustain higher level activation and become more dysfunctional,» Wherry says.
The underlying mechanism involves the activation of the immune system, resulting in local inflammation and proliferation of skin cells.
This program, resulting in shorter 3 ′ UTRs, is a characteristic of gene expression during immune cell activation and correlates with proliferation across diverse cell types and tissues.
Four separate teams have tried different drugs including sevelamer to reduce microbial translocation and immune activation in humans, so far with no significant benefits, according to results presented at the Conference on Retroviruses and Opportunistic Infections which was held in Boston in March.
That reaction results when a localized accumulation of immune complexes — antibodies bound to their antigens — is deposited in tissue and sets off an inflammatory response involving the infiltration and activation of immune cells, initially the neutrophil.
The immune cell measured is the basophil, and the blood test, the basophil activation test or BAT, requires only a small blood sample and provides quick results.
The evidence for immune activation was most prominent in the anterior cingulate cortex, a brain region involved in mood regulation and implicated in the biological origin of depression, confirming the results of a previous study that first identified altered microglial activation in medication - free MDD patients.
Without Caveolin - 1, the binding of viruses or bacteria to the B cell results in a reduced activation signal, which leads to a weakened immune response.
So were the immune homing signals that are produced as a result of NFkB activation.
Results showed that CD32 expression is rather a marker for activated, HIV infected CD4 T cells, since it was co-expressed with other molecules that characterize immune activation.
Obesity is associated with a low - grade inflammation of white adipose tissue (WAT) resulting from chronic activation of the innate immune system.
The detrimental effects of chronic immune activation, which is the result of HIV infection, have become increasingly clear.
The results suggest that environmental factors that alter the intestinal barrier may predispose individuals to an increased susceptibility to gluten through a bystander immune activation to intestinal microbiota.
It's a problem of persistent immune activation, which can be the result of many factors from environmental toxins to high stress to genetic predisposition.
... test identifies food items that result in release of inflammatory markers and activation of innate immune cells
The result of an imbalance in cortisol, otherwise termed Hypothalamic Pituitary Adrenal (HPA) Axis dysregulation is weight gain, fatigue and brain fog, inflammation and immune system activation, digestive issues, restlessness, impaired sleep, decreased cognitive function, and mental health conditions, such as anxiety and depression.
Chronic infections can result in prolonged activation of the immune system, resulting in chronic fatigue.
What I feel would be optimal in preparation for a life - changing surgery is a breathing practice that will result in increased relaxation, decreased stress hormones in the bloodstream and an intentional activation of the immune system.
(a) Protective parenting will be associated with epigenetic regulation of inflammation via methylation of TNF resulting in a positive (+) association as well as with relative activation of innate vs. acquired immune responses via shifts in the relative proportion of different white blood cell types of different white blood cell types leading to a negative -LRB--) association.
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