Sentences with phrase «resulting phenotypic changes»

The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.

Not exact matches

At present, and based on what we know of the genetic regulation of development, these phenotypic changes in the gut are most likely the result of positive genetic changes in the genetic regulatory pathways controlling the development of the relevant anatomical features, i.e. they are novel positive, heritable genetic features producing a specific and functional novel anatomical structure within the Genus.

The results show the plants have great phenotypic plasticity and do not all change in the same ways.

Aneuploidy is responsible for the observed phenotypic changes, as chromosome loss restoring euploidy results in a wild - type phenotype.

Acclimatization refers to phenotypic changes by an organism to stresses in the natural environment that result in the readjustment of the organism's tolerance.

This phenotypic diversity is often the result of changes or loss of ancestral phenotypes or gain of novel phenotypes during evolution.