Sentences with phrase «resulting small molecules»

The bacteria break up large molecules that the host can not digest, and the host in turn absorbs many of the resulting small molecules for energy and nutrients.

Not exact matches

Unpublished results from the researchers hint that significantly fewer anomalies are seen in iPS cells created via virus - free reprogramming strategies, such as ones that use proteins or small - molecule drugs.

Initial results were discouraging: attempts to simply replace the protein therapies with small - molecule drugs that hit the same targets largely failed, says Saeed Fatenejad, a rheumatologist at Pfizer who is responsible for clinical development of tasocitinib.

A global analysis of metabolites and small molecules in urine samples from patients with adrenal cancer has identified four biochemicals that, when measured together, can distinguish malignant from benign adrenal tumors, according to study results presented at the 2015 Annual Clinical Congress of the American College of Surgeons.

The new - generation microporous material designed at Dartmouth is the result of chemically stitching small organic molecules to form a framework that scrubs the isotope from water.

As a result, only a small fraction of atomic elements, along with a select few diatomic molecules, have been cooled in this manner.

All three labs used a technique that Tuschl had developed to clone small RNA molecules, and their results — 103 new microRNA genes in all — were published together in the journal Science in October 2001.

We're convinced, based on this result, that we can put together a platform that would enable on - demand assembly of complex small molecules.

«Now that we have this quantifiable result, that with only 12 building blocks we can make more than 75 percent of polyenes, we are committed to figuring out a global collection of building blocks — how to make them, how to put them together — to create a generalized approach for small - molecule synthesis.»

«Traditionally, scientists have theorized fairly narrow limits on which proteins can be targeted with small - molecule ligands, but our results suggest that those boundaries are much wider,» said Cravatt.

«We analyzed these small molecules in the blood and urine of non-diabetic patients with chronic kidney disease and compared the results to samples obtained from a group of healthy individuals,» said Stein Hallan, M.D., first author of the study published in EBioMedicine.

This material succeeds where both large and small molecules have failed, the net result being a clear biodegradable plastic with desirable mechanical properties, manufactured from a sustainable and natural resource.

Dr. Disney and his group studied the structure of the RNA that resulted from the C9ORF72 mutation, and then designed the lead small - molecules.

Indeed, inhibiting CXCR4 function systemically with the small molecule antagonist plerixafor results in the peripheral mobilization of hematopoetic stem cells, thus mitigating the potential of such therapy for long - term anti-retroviral therapy.

The results of previous blind tests, in 1999, 2001, 2004, 2007 and 2010, demonstrated that the crystal structures of small organic molecules can be predicted under favourable conditions.

Identification of small molecule inhibitors of Cisplatin - induced hair cell death: results of a 10,000 compound screen in the zebrafish lateral line.

Previous collaborations between CBCS and the inventors of CETSA resulted in the reformatting of the original CETSA method to a format amenable for High - Throughput Screening (HTS) as well as the successful performance of the very first small molecule screening campaign based on CETSA.

The next step may be to follow up on these promising results and customize the small molecules for a higher affinity fit.

Once the Vanderbilt small molecule library has been screened for potential modulators of the Y4 receptor, I will use the results to design efficient and accurate descriptors that can be used with artificial neural networks to predict activity at the Y4 receptor based on a small molecule's structural properties.

Results with small, electrically charged cyanide ions and water molecules reveal that water zips around ions to a greater extent than expected.

The combined treatment of ActD with leptomycin B, a small molecule nuclear export inhibitor, has been shown to successfully lead to the accumulation of transcriptionally active p53 in the nuclei of human papillomavirus positive cervical carcinoma cells, resulting in apoptosis of the cells [16].

The observations showed that the interactions and resulting concentration of TDP - 43 molecules depend on a small corkscrew - shaped part of the protein's C - terminal domain termed a helix.

Energy metabolism and the production of Reactive Oxygen Species (very small molecules that can result in significant damage to cell structures, of which include oxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these conditions.

I'm not sure offhand of the importance of this, but more rapid cooling from more rapid ascent would reduce the distances over which molecules can diffuse during the time periods involved, which would tend to isolate the effects of the particles from each other, so that more haze particles could go on to become cloud droplets, resulting in smaller and more numerous cloud droplets.

That results in higher density and heavier air which must then fall.The same number of molecules in a smaller space.

ferd berple says: ``... increasing the weight of N2O2 in the atmosphere will increase the surface temperature, as more and more molecules are packed into a smaller volume, resulting in a net increase in energy per cubic meter of atmosphere at the surface, which we measure as an increase in temperature.»

That gravity is responsible for the 33K in unexplained heating and contrary to the assumptions of the radiative transfer model, increasing the weight of N2O2 in the atmosphere will increase the surface temperature, as more and more molecules are packed into a smaller volume, resulting in a net increase in energy per cubic meter of atmosphere at the surface, which we measure as an increase in temperature.

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