Sentences with phrase «results in rodent»

Rats are not people, of course, and test results in rodents are never perfectly translated in people (if at all).

Past studies of high - fat diets have yielded somewhat mixed results in rodents, says Ralph DiLeone, a neurobiologist at Yale University.

Not exact matches

As in rodents and monkeys fed 18:3 n − 3 - deficient diets (34, 35, 38 — 40), the higher 22:5 n − 6 concentrations resulted in central nervous system total n − 6 plus n − 3 fatty acid concentrations similar to those in the control animals.

We expanded mental health services in schools through partnership with Say Yes and others; maintained an active and robust rodent control program that is having positive results in communities across the county; continued a very popular rabies clinic program that has been attended by thousands of appreciative pets (and owners); and, along with partners, created the innovative Erie County Health Mall to improve local health outcomes.

Despite promising results from past studies in rodents and nonhuman primates, testing the antisense strategy in people carried big unknowns.

«The project's goal is to accelerate the development of technologies for mapping the brain's circuitry in animal models, specifically in the marmoset monkey, whose neural circuits are much closer to human compared with rodent models, and to connect the results to the diagnosis and treatment of human neurological disorders and mental illness.»

UCI's Charles Limoli and colleagues found that exposure to highly energetic charged particles — much like those found in the galactic cosmic rays that will bombard astronauts during extended spaceflights — causes significant long - term brain damage in test rodents, resulting in cognitive impairments and dementia.

Studies of rodents have suggested that pregnancy results in greater resilience to stress.

Results so far in rodents have been encouraging.

In previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkIn previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkin the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkin the hippocampus» memory circuit and increased neuronal signaling networks.

Insofar, the results are also relevant for humans: 85 % of the long - lived rodents» genes are identical to human DNA, but in contrast to humans that are rather prone to illness, long - lived rodents have a very low risk to come down with age - related diseases.

In rodents, toxo's natural hosts, the parasite gets into the brain and makes the animals less fearful, resulting in them taking more riskIn rodents, toxo's natural hosts, the parasite gets into the brain and makes the animals less fearful, resulting in them taking more riskin them taking more risks.

The research from the University of Sydney's School of Life and Environmental Sciences found there could be decreases in the cover of the dominant plant, spinifex, and a resulting decrease in seeding — and that introduced cats and foxes pose one of the major threats to seed - eating rodents.

However, stimulation of targets in the lateral hypothalamus in rodents during learning resulted in improved performance on tests of subsequent memory.11

This pattern may result in more rodent - borne diseases.

- Modelling Human Disease in Rodents with CRISPR / Cas9 Genome Editing: June 27th - Why do the results discovered using genetically engineered mice sometimes fail to translate to humans?

PsychoGenics has pioneered the translation of rodent behavioral responses into robust, high throughput, high content phenotyping and its drug discovery platforms, SmartCube ®, NeuroCube ®, and PhenoCube ® have led to shared risk partnerships with major pharma companies such as Sunovion and Roche and resulted in the discovery of several novel compounds now in clinical trials or advanced preclinical development.

That is also why you see dramatic results in yeast, fly, rodent models but there is rarely a much longer lived specie (albeit the reason being it takes many years to follow the results, scientists can't wait an entire life to know if their intervention lengthens the lifespan of a long - lived specie or not.

The results were obtained from mice and human stem cells in cultivated brain tissue, and from a series of rodent models for human neurodegenerative diseases and acute brain injuries.

Combining his ecotoxicology expertise with government relations responsibilities has resulted in the successful registration and authorized use of seven conservation rodenticide bait products for removal of rodents from islands in 5 countries.

Finally, combining the results of PET imaging of declines in these different neuromodulator systems with behavioral studies in patients with Parkinson's disease and rodents with experimental damage to those systems helps us understand how they contribute to both cognitive deficits and the risk for falls.

She will discuss the Systems Biology approaches currently used to understand the Omics results from space flight model systems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital organs).

In large quantities, acrylamide is a known cancer - causing chemical according to results from tests with rodents, Lichtenfeld explained.

Undomesticated cats hunt, which results in a diet consisting of small animals such as rodents and lizards, insects, and small birds — prey that is high in fat and protein, and very low in carbohydrates.

The resulting rebound in rabbit and rodent numbers, however, has had its own disastrous impact.

Some dogs, cats, rabbits and rodents like to nibble on cords, which can result in serious burns and can cause a fire.

«The results,» wrote George, «established a basis for examining the possibility that cat predation may result in depleted winter populations of microtine rodents and other prey of Red - tailed Hawks, Marsh Hawks, and American Kestrels.»

Though rattlesnakes can be dangerous if provoked, they provide humans with a tremendous service by reducing the number of disease carrying rodents and other pest species that would otherwise result in a large social and economic stress.

Additionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring.

Some of these effects in rodents might be explained by the nipple switching facilitated by arched - back nursing, which results in increased tactile stimulation (19).

Infected rodents don't last long in the presence of a cat and their consumption ultimately results in a bowel movement that contains thousands of microscopic oocysts, the parasite's infective stage, thus completing the cycle.

If the rodent is only partially thawed, it can result in dramatic health issues for the snake.

But nearly every homeowner's insurance policy will cover sudden and unexpected damage that is caused by pests or infestation, or that results in the damage to your property by rodents after other sudden and unexpected damage to your home.

To compensate, the rodents» livers produced too many cells, resulting in liver damage that led to liver cancer, the researchers found.

Rhinos play an important role in the environment, dispersing seeds and keeping vegetation — and as a result, rodents and snakes — under control.

Although early - life adversity results in hyperreactivity of the sympathetic nervous system (SNS) and hypothalamic — pituitary — adrenal (HPA) axis in rodents, evidence from human studies is inconsistent.

Stress exposure in mature rodents is associated with immediate, but not lasting, changes in stress response systems (5, 6), suggesting the presence of an early sensitive period when exposure to adverse environments results in long - term changes in physiological stress response system functioning.

Several investigators using mother — infant separation paradigms in rodents, one of the most frequently used paradigms to examine the effects of early stress, have noted that separation resulted in subtle disruptions in the quality of maternal — pup interaction.

A further study on the semi-precocious rodent Octodon degus [132] showed that short, repeated separations in the first three weeks of life resulted in significant alterations of density of neurons releasing corticotropin releasing factor (CRF) in brain regions involved in emotion regulation.

Around the time of birth in most mammals, changes to the hormonal milieu including fluctuating levels of estrogen, 19,20 progesterone19, 20, prolactin21 and oxytocin22 trigger a cascade of neurological adaptations that result in typical maternal behaviour.23 Numan, and colleagues,24 - 29 have demonstrated that the neurobiology of mothering in rodents relies heavily on projections from the medial preoptic area of the hypothalamus and bed nucleus of the stria terminalis, as well as fibres from surrounding sensory, limbic and cortical systems.