The preventative won't affect antigen test
results and it can prevent the spread
of heartworm in the shelter and prevent infection in an animal, even if
microfilaria (heartworm larvae) are already present in the bloodstream.
Diagnosis
of canine dirofilariosis in animals which originate from a low - endemic region is difficult for 3 main reasons: 1) possible absence
of circulating
microfilariae (occult disease), 2) high frequency
of a low number
of adults, which in turn produces false negative
results, using either ELISA or latex agglutination test, 3) possible false sero - positive
results, due to cross-reaction with adult antigens
of Dirofilaria (Nochtiella) repens (Schrey, 1996), the agent
of subcutaneous dirofilariasis causing chronic pruritic dermatitis in dogs (Tarello, 1999).