Sentences with phrase «results of the new trial»

Results of a new trial of treatments for chronic whiplash pain, published in The Lancet, suggest that expensive, intense physiotherapy sessions do not show any additional benefit over a single physiotherapy session of education and advice with phone follow - up.

The scanners will not be installed in Terminals 1 and 3 as originally announced, until the results of the new trial in T2 are ascertained.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

In particular, the complaint alleges that throughout the Class Period, defendants made materially false and / or misleading statements and / or failed to disclose that (1) the trials for GED - 0301 suffered from fatal design defects, such that GED - 0301 had failed to demonstrate meaningful clinical efficacy; (2) the growth of Otezla sales had dramatically slowed during Celgene's third fiscal quarter of 2017; and (3) the clinical and nonclinical pharmacology data in Celgene's new drug application («NDA») for Ozanimod were insufficient to permit a complete review by the FDA, which resulted in the FDA issuing a refusal to file letter to Celgene regarding the NDA.

And we settled the case, because no one wanted a three - year appeal that would result in a new trial four to five years from the date of the current trial.

Cologuard was approved by the FDA in August 2014 and results from Exact Sciences» prospective 90 - site, point - in - time, 10,000 - patient pivotal trial were published in the New England Journal of Medicine in March 2014.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Since 2008, Good Cookies like YOU have helped fund dozens of pediatric cancer research grants, resulting in NINE promising new treatments moving to clinical trial, now available to children with cancer.

As a result of the successful trial, a new IX - GA - 4057 X-ray system has been permanently installed on Anatolia's bulk packaging line and carries out a final product inspection — removing any foreign bodies which have «slipped» through the upstream inspection process.

«The results of this [new] trial are so compelling, and the problem of the increasing prevalence of peanut allergy so alarming.»

Labour suggested the new guidelines were a result of concerns over the Twitter joke trial, in which a man was prosecuted or jokingly threatening to blow up an airport - a decision Starmer supported.

He was a supervising agent in the New York investigation of the Cosa Nostra criminal network that resulted in the Mafia Commission Trial of 1985 — 1986.

New court precedent has impacted the cases of New York lawmakers before: precedent set by the U.S. Court of Appeals for the Second Circuit eventually resulted in a new trial being ordered for Skelos» predecessor in the Senate, Joseph BruNew court precedent has impacted the cases of New York lawmakers before: precedent set by the U.S. Court of Appeals for the Second Circuit eventually resulted in a new trial being ordered for Skelos» predecessor in the Senate, Joseph BruNew York lawmakers before: precedent set by the U.S. Court of Appeals for the Second Circuit eventually resulted in a new trial being ordered for Skelos» predecessor in the Senate, Joseph Brunew trial being ordered for Skelos» predecessor in the Senate, Joseph Bruno.

In June, the U.S. Supreme Court overturned the corruption conviction of former Virginia Gov. Bob McDonnell in a ruling that could result in new trials for Silver and Skelos.

What's being revealed at trial of how the pay - to - play culture works in New York, which has resulted in a $ 30 million political war chest for the governor, is a case in point.

The trial of Ciminelli and Laipple and others is slated to start in New York on June 11, and its results could be part of this fall's election as Gov. Andrew M. Cuomo seeks re-election.

He named the challenges militating against cocoa production in the country as the unreliable supply of inputs to farmers as a direct result of the «free» input policy adopted by the government, new brands of chemical inputs released to cocoa farmers in Ghana without adequate trials and research by designated institutions, low producer prices paid to farmers and the politicisation of the mass spraying and fertiliser distribution programme.

Adding abiraterone to hormone therapy at the start of treatment for prostate cancer improves survival by 37 per cent, according to the results of one of the largest ever clinical trials for prostate cancer presented at the 2017 ASCO Annual Meeting in Chicago and published in the New England Journal of Medicine.

Results of the trial, reported in the May 31 issue of the New England Journal of Medicine and presented at the American Society for Clinical Oncology 2015 annual meeting, also showed that after a year, the nivolumab group had nearly double the survival rate (42 percent) of the chemotherapy patients (24 percent).

A University of Manchester led trial of a new psoriasis drug has resulted in 40 percent of people showing a complete clearance of psoriatic plaques after 12 weeks of treatment and over 90 percent showing improvement.

Boni E. Elewski, M.D., professor of dermatology, is the principal investigator of the Efficacy of Response And Safety of two fixed secUkinumab REgimens in psoriasis (ERASURE) trial, one of two studies in the recent New England Journal of Medicine article «Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials.»

Dr. Del Maestro adds, «Yong and colleagues at the University of Calgary have begun to unravel the complex interaction of the microglia with the brain tumor cells, resulting not only in furthering our understanding, but providing a new concept and drug which can now be immediately assessed in clinical trials.»

The much - awaited results of a large randomized trial comparing three approaches to localized prostate cancer were published in The New England Journal of Medicine today.

«The results of the phase III clinical trial show that a target fusion biopsy detects more clinically significant prostate cancer,» said Art Rastinehad, DO, principal investigator of the study and director of interventonal urologic oncology at North Shore - LIJ's Arthur Smith Institute for Urology, in New Hyde Park, NY.

«These exciting results indicate that there is a new standard of care option for a population of head and neck cancer patients with no other treatment options,» said the trial's international co-chair Robert Ferris, M.D., Ph.D., UPMC Endowed Professor, and chief of the Division of Head and Neck Surgery and co-leader of the Cancer Immunology Program at UPCI.

In a trio of studies to be presented at the 57th American Society of Hematology (ASH) Annual Meeting and Exposition in Orlando, investigators at Dana - Farber Cancer Institute will present the results of clinical trials showing that new drug combinations can significantly extend the time in which multiple myeloma is kept in check in patients with relapsed or treatment - resistant forms of the disease.

People diagnosed with cancer gained 3.34 million years of life thanks to cancer clinical trials run by SWOG and supported with public funds, according to new study results to be presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO), the world's largest clinical cancer research meeting.

Promising results from the new trial would be a major step forward for a field that has long been criticized for studies that are poorly designed, incomplete or lack control - group comparisons, as well as for the peddling of unproved therapies in many clinics worldwide.

The final results from an international clinical trial involving nearly 2,000 patients with Crohn's disease support the use of a new management strategy referred to as accelerated step - care as a best practice for the care of active Crohn's disease.

The new study helps explain why so many results in animal studies don't hold up in human trials, says Malcolm Macleod, a neurologist at the University of Edinburgh.

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

The results of the trial have not yet been published, but the volunteers seemed to be healthy and happy after adjusting to the new diet, says Hong Liu, the lead researcher on the project.

«For example, a non-blind trial of a new drug might conclude that it is way more effective than a placebo, when in fact the drug's true effect is rather modest, simply because the researchers» expectations biased the results.»

The paper also reflects the diminished role of aspirin in AF stroke prevention guidelines, various improvements in angioplasty / stent technology, and the results of new randomised trials including WOEST.

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

Results of a new survey reveal that most cancer patients don't realize that participation in a clinical trial is a treatment option.

The results of the phase III clinical trial were published November 29, 2017 in the New England Journal of Medicine.

«New report calls into question effectiveness of pregnancy anti-nausea drug: Researchers reanalyze clinical trial results reported in 2010.»

Among the new voluntary efforts by pharmaceutical companies to post clinical trial data, the Association of the British Pharmaceutical Industry, one of the trade groups behind last week's proposal, will recommend that its members post trial results on a World Health Organization (WHO) global trials database that WHO hopes to establish in July.

What most encourages Black, in addition to the new breakthrough in blood - brain barrier research, are the results of a Phase 1 clinical trial of an anticancer vaccine that began at the institute in 1998.

The new six - year study, «Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18 - month randomized clinical trial,» involved 54 adults and was led by Shaun Eack, Ph.D., M.S.W., Pitt's David E. Epperson Professor of Social Work and Psychiatry, and Nancy Minshew, M.D., Pitt professor of psychiatry and neurology.

The first - of - its - kind study found the dual treatments to be safe and elicit a clinical response in patients, according to new results from a phase I trial to be presented at the AACR Annual Meeting 2015 on April 19.

«The promising safety results of these early trials set the stage for additional HCQ trials in different cancers, and trials involving new autophagy inhibitors that are being developed by pharmaceutical companies,» said Amaravadi.

Tulane University researchers have developed a new drug that is effective against non-severe cases of malaria, according to results from an FDA - supervised clinical trial published in the latest issue of The Lancet Infectious Diseases.

Pembrolizumab is set to become a new option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of Medicinew option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of MediciNew England Journal of Medicine.

New clinical trial results show that transplantation of pancreatic islets — cell clusters that contain insulin - producing cells — prevents severe, potentially life - threatening drops in blood sugar in people with type 1 diabetes.

The results of the trial, which compared a combination of checkpoint inhibitors ipilimumab and nivolumab against ipilimumab alone in previously untreated patients, were presented today at the 2015 Annual Meeting of the American Association for Cancer Research and have been simultaneously published in the New England Journal of Medicine.

Although the publication of results of clinical trials carried out in the USA within 12 months of their completion has been mandatory since 2007, an astoundingly high number of Phase III radiotherapy trials did not do so, according to new research to be presented at the ESTRO 35 conference today (Saturday).

The results of the Phase 3 clinical trial were published in the New England Journal of Medicine.

New results from a clinical trial involving more than 900 military veterans at high risk for keratinocyte carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75 percent within a year.