It tries to produce good
results with a low level of risk by spreading your money among Canadian and foreign stocks as well as bonds.
Not exact matches
While socializing
with co-workers led to higher
levels of fatigue, talking on the phone
with a friend, on the other hand,
resulted in
lower levels of fatigue.
Actual
results, including
with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can
result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products
results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that
result in higher production costs and
lower margins; our ability to
lower costs; the risk that our
results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders
with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated
with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products,
resulting in
lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations,
resulting in significant additional costs, including costs associated
with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks
resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements
with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory
levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products
with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated
with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated
with ongoing litigation; and other factors discussed in our filings
with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed
with the SEC.
The
result of Canada's
low level of productivity is, among other things, a relative weakness in GDP per capita, as compared
with other members of the G7 and OECD.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial
results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations
with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of
lowering prices or reducing the number of insured patients; the possibility of unfavorable
results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination
with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed
with the U.S. Securities and Exchange Commission (the SEC).
«Although revenue declined, the first quarter of 2016 continued
with a trend of
low -
level shipments growth on a global
level with a variation in
results by region,» said Jeffrey Hewitt, research vice president at Gartner.
The
resulting high
level of interest rates in the wholesale money market, the main source of funds for lenders such as mortgage managers, made it difficult for potential new lenders to compete
with banks, who had access to
low - cost retail funding.
What the two groups have found is the beginnings of a detection «bump»: ATLAS team quotes a tentative
result at 125 - 126GeV
with a statistical significance of 3.6 σ (3.6 standard deviations); the CMS team finds one at 124GeV at a
lower confidence
level of 2.6 σ.
The
lower levels of baseline sugar sweetened drink consumption in the UK compared
with the US may in part explain why the effect on obesity that we estimate in the UK is much less than that estimated in the US.12 The differences
with respect to other modelling studies may also be partly explained by their use of higher own price elasticity values for sugar sweetened drinks than we have calculated and used here.18 22 52 We can not make direct comparisons between the
results of our study and the
results of recent studies of the effect of reducing sugar sweetened drink consumption on body weight in children, 5 7 as the relation between energy balance and change in body mass index in children who are growing is different from that in adults.
As the
result from the study shows the glucose
levels might increase if having caffeine together
with a meal
with a high amount of carbohydrates but there is no indication what the impact is for people who eat according to a
low carb diet.
what they have to do is be professional about their line of work but they can simply view it as their work and if you do nt like their performance as employee of the brand, you can demand change and criticise but just being disappointed
with the
results do nt give the fans the right to insult on such a
low level like some guys on here and in this kind of view insulting a man who worked 20 years absolutely professionally for a club is just downright wrong, i never said you shouldnt criticise him
Children
with negative or
low antibody
levels and even moderate
levels may not actually be allergic to those foods, so those test
results must be interpreted based on the symptoms the child has when he eats those foods.
As well as bonding
with the baby when sharing the breastfeeding, lesbian parents report enjoying the effects of the relaxation hormones released when lactating (
resulting in
lower stress
levels in the parent and baby), the flexibility of having two nursing parents when one needs to absent herself occasionally or when returning to work, and the health benefits of breastfeeding such as
lower rates of breast cancer, ovarian cancer and Type II diabetes (8), (9).
«
Results: Formula use at birth or short breastfeeding duration were significantly associated
with low levels of nurturance, high
levels of reported anxiety and increased maternal use of Parent - led routines.
In two controlled trials conducted in Honduras, allocation to exclusive breastfeeding to six months of age compared
with mixed breastfeeding from four to six months
resulted in
lower haemoglobin, ferritin, and hematocrit
levels in infants, but no differences were found in anthropometric or morbidity outcomes, and mothers resumed menses later and lost more weight
Restructuring library services to this
lower funding
level would
result in major curtailment in access to public library service,
with reduced open hours system - wide and the loss of over 100 full - time equivalent (FTE) positions.
The 2006
result was one of Labour's worst local election
results in London,
with its share of the vote (30.1 %), its number of council seats (684) and number of councils (7) all at their
lowest levels since 1968.
The
results of the study show that more than half of the patients
with bipolar disorder who had elevated or
low levels of cortisol in the blood, also had depression.
The study also shows that people who had
low cortisol
levels, on average, have had their disease longer than those
with high cortisol
levels, which could suggest that chronic stress in bipolar disorder can lead to an «exhaustion» of the stress system
with reduced cortisol
levels as a
result.
After six cycles of attempting to conceive,
results did not differ significantly between women
with low levels and normal
levels of anti-Müllerian hormone — a 65 - percent chance of conception, compared to a 62 - percent chance.
As a
result of a decade of drought, the dam is now operating at only 30 percent of its capacity, said Matthews, and new mechanisms have been added to cope
with the
lower water
levels.
What's interesting about our
results is that also
low cortisol
levels were associated
with a considerable increase in negative health consequences,» says Martin Maripuu.
The
results showed that patients
with diabetes had substantially
lower levels of substance P in tear film samples, compared to healthy controls.
While NIOSH and NCI said in a joint statement that «it will be up to the regulators to determine whether the current acceptable
level should be
lowered,» they added that the DEMS
results «should be broadly applicable to other workers
with similar
levels of exposure to diesel exhaust.»
While early research found that e-cigarettes
resulted in
lower levels of plasma nicotine than conventional cigarettes, more recent research demonstrated that experienced users can attain nicotine absorption similar to that
with conventional cigarettes.
Results show that higher
levels of fragmented sleep and
lower sleep efficiency were associated
with a 40 to 50 percent increase in the odds of clinically significant decline in executive function, which was similar in magnitude to the effect of a five - year increase in age.
While the
results did not detect dark matter particles — known as «weakly interacting massive particles» or «WIMPs» — the combination of record
low radioactivity
levels with the size of the detector implies an excellent discovery potential in the years to come.
«We no longer consider this the gold standard,» Boyle says, as horses
with low levels of bacteria may still be carriers but not give a positive
result on this test.
Conversely, infecting the mice
with bacteria that produced
low levels of c - di - GMP
resulted in a substantial reduction in P. aeruginosa abiding in these organs.
As a
result, the benthos population became dominated by species that could survive
with much
lower oxygen
levels throughout the 1960s.
The one year
results, revealed today, show that the remede ® system led to substantial benefits in sleep parameters including a reduction in AHI, a reduction in the time spent
with low blood oxygen
levels overnight, and improvements in sleep efficiency and REM sleep.
The researchers found no statistically significant difference between rates of asthma (including childhood - onset asthma), atopic dermatitis, or IgE
levels in people
with or without any of the four genetic changes associated
with lower levels of 25 - hydroxyvitamin D. However, the
results do not exclude an association between the outcomes and
levels of 1,25 - dihydroxyvitamin D, the active form of the vitamin, and more work will be needed to determine if the
results hold true in non-European populations and in people
with vitamin D deficiency.
Analyzing the
results, the researchers found that people
with both relatively higher and
lower levels of cognitive ability show approximately equal
levels of intergroup bias, but towards different sets of groups.
The researchers began to detect
low levels of fungal infection in the fall, probably as a
result of bats coming in contact
with spores of the fungus inside the hibernacula.
The
results indicate, on a multinational
level across
low - and middle - income countries, that a diagnosis of psychosis is associated
with physical inactivity, especially among males.
«Although our study's
results may in part be explained by joint injuries associated
with high -
level physical activity in those
with a
lower 2D: 4D and the greater susceptibility of knee OA in response to injury than hip OA, they may also reflect hormonal influences on the growth of bone, cartilage, and soft tissue, which warrants further investigation.»
The researchers said
results showed that
levels of distress were
lower in children distracted
with cartoons, compared
with those distracted using the standard procedure.
The
results were conclusive: runners
with a higher genetic score had
lower levels of creatine kinase and myoglobin in their blood, that is, less damage to muscle fibres, compared to marathon runners
with a less favourable score.
To be sure of their
results, the researchers tested whether they held true in additional volunteers
with high and
low levels of IgE from Wales and further asthmatic families from Quebec.
The
results on the children's development from the first 12 months of this study were published in Pediatric Research in 2011, and showed improved attention and
lower heart rate in infants supplemented
with any
level of LCPUFA.
SEATTLE, WASHINGTON — When French scientists presented the
results from an Ebola drug trial at a press conference on Monday, they did so
with plenty of caveats, but their message was hopeful: The drug, favipiravir, appeared to
lower mortality in people
with low and medium - high
levels of virus in their blood, the researchers told journalists at the Conference on Retroviruses and Opportunistic Infections (CROI) here.
The
results also revealed that when the group of healthy men
with a
low level of liver fat consumed a high amount of sugar, their liver fat increased and their fat metabolism became similar to that of the men
with NAFLD.
The
results of the study show that HRV was reduced in association
with increases of 5 dB in noise exposure at both the higher and
lower noise
level ranges.
Among older patients
with diabetes whose treatment has
resulted in very
low hemoglobin A1c (HbA1c)
levels or blood pressure values, only 27 percent or fewer underwent medication deintensification, a lost opportunity to reduce overtreatment, according to an article published online by JAMA Internal Medicine.
Our study, along
with prior studies, supports the notion that «cognitive reserve»
resulting from early - life and lifelong education and cognitive stimulation may be a potent strategy for the primary prevention of dementia in both high - and
low - income countries around the world.21 However, it should be noted that the relationships among education, brain biology, and cognitive function are complex and likely multidirectional; for instance, a number of recent population - based studies have shown genetic links
with level of educational attainment, 22,23 and
with the risk for cognitive decline in later life.24 Higher
levels of educational attainment are also associated
with health behaviors (eg, physical activity, diet, and smoking), more cognitively - complex occupations, and better access to health care, all of which may play a role in decreasing lifetime dementia risk.
«These
results suggest
low levels of testosterone are associated
with more aggressive prostate cancer.
The
results were promising, showing that men receiving the programme were better able to manage conflict in a non-violent way, and
with some suggestion that
levels of violence were
lower.
Measurements of air on the beaches outside Chittagong show very high
levels,
with somewhat
lower results in the city.
In summer, southerly transport associated
with clean maritime air masses and cloudy weather leads to relatively
low surface ozone
levels, often
resulting in the annual minimum (Wang et al., 2009; Lam et al., 2001).
Stimulation of BP
with the Tie2 ligand Ang1
resulted in detectable Tie2 phosphorylation, albeit again at considerably
lower levels as in EC (Fig. 1e — h).