Sentences with phrase «retinal angiogenesis»
Yet, this delay of retinal angiogenesis can be compensated and pericyte Tie2 appears to be dispensable for homeostatic maintenance of the vasculature in adult mice.
http://www.nature.com/
Whole mount retinal image analysis of P4, P6 and adult mice identified a transient delay of retinal vascularization characterized by a reduction of MVD at peak retinal angiogenesis (P4; at this stage no difference in pericyte coverage) and a reduction of pericyte coverage upon completion of lateral angiogenesis (P6; at this stage no difference in MVD)(Fig. 4c — f).
Second, Tie2 deletion in pericytes caused a mild and transient developmental delay of postnatal retinal angiogenesis and vessel maturation.
Chronic experimental hypoxia kills photoreceptors in adult rat retina [14] and can lead to retinal angiogenesis [15].
Not exact matches
Our objective is to determine whether this mutation is involved in AMD by (1) understanding the functional consequences of this genomic variation on expression of COL8A1 and / or its neighbor genes, and (2) investigating photoreceptors and RPE cell survival, retinal and choroidal angiogenesis, structure integrity of the choroid / Bruch's membrane, and the quality of the vision, in organisms with the COL8A1 mutation.
The authors are planning future studies exploring methods for efficient retinal delivery of Ro5 - 3335 and the relationship between RUNX1 and VEGF, as both factors play a role in angiogenesis.