Sentences with phrase «retinal layer»

Focal and multifocal types manifest as linear folds and «rosettes» of tissue in the inner (sensory) retinal layer whereas in geographic forms there are larger areas of defective retinal development that appear as large irregular or horseshoe - shaped areas of mixed hyper - or hyporeflectivity in the central retina.

These cells protect and nourish the retina, remove waste products, prevent new blood vessel growth into the retinal layer, and absorb light not absorbed by the photoreceptor cells; these actions prevent the scattering of the light and enhance clarity of vision.

Current clinical gold - standard methods for assessing the structural integrity of nerve fibers damaged by glaucoma are only able to detect complete loss of those fibers from the retinal layer within the eye.

Here the so - called bipolar cells play a central role, as the first retinal layer to process the output of the light - sensitive cells in the eye.

They found high concentrations of both RNAs in a retinal layer containing neurons that connect to the suprachiasmatic nucleus, a brain region known to be important in the circadian rhythm.

«This gives us a non-invasive technique for looking into the retinal layers, so that we can detect minute changes early on,» explains Bogunovic.

Both unmodified and genetically modified groups were found to have cells that migrated and survived in two distinct locations: (i) as a separate, nearly continuous, subretinal layer lying between the host RPE and photoreceptors, and (ii) as individual cells distributed throughout the neurosensory retina, especially within the inner retinal layers (Figure 5A).

(A) High quality section through a wildtype canine retina shows the normal retinal layers and architecture.

Not exact matches

A layer of cells called the retinal pigment epithelium (RPE) is essential for supporting and nourishing the retina cells that capture light for vision.

Shatz now had indirect evidence that the layers were formed in response to retinal signaling, coded for not by experience but by genes.

The retinal pigment epithelium (RPE) is a single layer of cells that accomplishes multiple functions, such as providing survival molecules that prevent photoreceptors from dying.

The cells transformed into the six major types of retinal cells and spontaneously arranged themselves into a layered cup - like structure, mimicking the adult retina (Nature, DOI: 10.1038 / nature09941).

First, the bottom layer of the network receives raw data representing pixelated images or multitonal sounds, and like retinal cells, neurons fire if they detect contrasts in their patch of the data, such as a switch from light to dark.

Vanessa Restrepo - Schild led the team in the development of a new synthetic, double layered retina which closely mimics the natural human retinal process.

The middle layer is a one - cell - thick sheet known as the retinal pigment epithelium, or RPE.

In the movie, the cells — made to glow green — push out before inverting and forming two different layers: the first, the retinal cells, and the second, the neurons.

The black layer on top of the photoreceptors is retinal pigment epithelium.

In wild - type, retinal ganglion cell layer (GCL), inner nuclear layer (INL), inner plexiform layer (IPL), and nuclear layers of rod and cone photoreceptors are distinct, and rod outer segment (OS) is observed at the outer-most layer of the retina.

Using this technology that enables visualization of individual retinal ganglion cells and the vasculature supplying them, they are aiming to elucidate the role of vascular insult to the nerve fiber layer in glaucoma pathogenesis.

In Figure 5O, the number of rod photoreceptor, inner nuclear layer, and retinal ganglion cells were determined by counting the nuclei of cells expressing XAP2, Calretinin, or in the RGC layer, respectively.

When transplanted to the subretinal space of mice lacking functional photoreceptors, human embryonic stem cells directed toward a retinal lineage integrate into the outer nuclear layer, express photoreceptor markers, and restore a light response as determined by the electroretinogram (ERG)[5].

The retinal pigment epithelium (RPE) is a layer of cells next to the retina that are metabolically coupled to the retina's photoreceptor neurons.

The RPE is a single layer of cells lining the back of the retina that is vital to the functioning of the retinal photoreceptor cells, and thus vision itself.

So, with that in mind, with this new understanding of fundamental biology, the group went back into the engineering side and said well, what can we do to image «off» retinal ganglion cell layers of the inner plexiform layer, and also to design a new visual field exam that could measure the «off» retinal ganglion cells separately from the «on» retinal ganglion cells?

Quantitative measurements on the inner retina reveal that despite being scattering in the far - field, retinal tissue possesses a high ability to transfer an image from its inner surface to the back of the outer nuclear layer.

The secondary endpoint of change in thickness of the temporal quadrant and papillomacular bundle of the retinal nerve fiber layer from baseline to week 48 demonstrated a large statistically significant difference (p = 0.0359) between all GS010 - treated eyes and all sham - treated eyes, with untreated eyes showing a loss of 3.4 μm while treated eyes showed a limited loss of 0.6 μm.

Shatz's first major scientific finding was that this layering of neurons in the LGN began before birth, in response to repeated bursts of spontaneous firing by retinal ganglion cells, which spread in waves across the retina.

(C) Retinal section from the same eye used in panel A stained with proliferating cell nuclear antigen (PCNA) revealing occasional dividing cells in the RPE - L layer and inner retina at P150 (arrows).

Histological examination at 150 days postnatal showed hNPC had formed a nearly continuous pigmented layer between the neural retina and retinal pigment epithelium, as well as distributed within the inner retina.

Behind the photoreceptors is another layer of cells called retinal pigment epithelium (RPE), which support the rods and cones by delivering nutrients from the bloodstream and removing waste that the rods and cones generate.

INL: inner nuclear layer; IS: inner segments; ONL: outer nuclear layer; RGC: retinal ganglion cell layer; RPE - L: RPE - like layer.

SD - OCT demonstrated statistically significant preservation of both retinal ganglion cells and retinal fiber layer in treated eyes vs. untreated eyes

The treatment could help people who have a fault in a gene called RPE65, which causes problems in the retinal pigment epithelium (RPE), a thin layer of cells that support and nourish photoreceptors.

Third place went to Charlie Granger, a PhD candidate in optics, who used adaptive optics technology to show the natural fluorescence of retinal pigment epithelial cells, which form a layer only one cell deep, on the backside of the eye's light - sensitive retina.

The preservation of these layers 13 weeks after iPS - RPE cell injection suggests that the transplantation of these cells preserves retinal structure.

To assess the topography of retinal function in grafted versus non-grafted eyes we employed functional anatomy to look at the activation of inter-neurons of the inner nuclear layer (INL).

The progression of retinal dystrophy in the RCS rat is such that by 13 weeks post-graft most of the ONL has disappeared [33] and the photoreceptor outer segment layer is reduced to a debris zone [40], a finding we observed in dystrophic controls.

Scale bars: Coronal sections, 50 µm; whole - mount images of the inner nuclear and retinal ganglion cell layers, 200 µm.

The induction of c - Fos expression in the inner nuclear layer (INL) and ganglion cell layer (GCL) of the retina in response to light is an indication of functioning retinal circuitry.

The back of the eye is lined with a layer of retinal cells which are stimulated by light passing into the eye through the lens.

Progressive Retinal Atrophy (PRA) is an inherited disease of the retina (tissue layer at the back of the eye containing the rods and cones) where the retina slowly degenerates with time.

The second most common blindness - causing disorder in cats, he says, is retinal detachment, a condition in which the retina becomes separated from its underlying tissue, typically resulting from a leakage or oversupply of fluid between the two layers.

Progressive Retinal Atrophy (or P.R.A.) is a degeneration of the layers of the retina that are responsible for vision.

Progressive Retinal Atrophy (or PRA) is a degeneration of the layers of the retina that are responsible for vision.

Retinal detachment is a condition that occurs when the inner layers of the retina separate from underlying pigmented layers.

The ERG assesses the function of the retina, the light - sensitive layer of the eye; the ultrasound examination looks for retinal detachment.

Typical changes include attenuation of the blood vessels of the retina, increased reflectivity of the tapetal layer as a result of retinal thinning and atrophy of the optic disc.

Layers of the retina: RPE, retinal pigment epithelium; PR, photoreceptors; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer; NFL, nerve fiber layer.

When looking through the Fujifilm FP - 100c instant color film datasheets, the similarities between the layering of materials in the film and the layering of cells in the retinal is striking.

Retinal detachment involves the retina of the eye peeling away from the underlying layer of support tissue.