Sentences with phrase «retroviruses containing»
To derive iPS cells from primary NPCs, EGFP - positive NPCs were infected with the retrovirus containing 4 factors.
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This is a model of a retrovirus capsid hexamer, showing the conserved beta - hairpin domains common to most kinds of retroviruses (circled) and a pocket containing additional sites thought to affect recognition of lentiviruses by the TRIM5 anti-viral defense proteins of old world monkeys (arrow).
Pig cells contain multiple copies of embedded viruses called porcine endogenous retroviruses, or PERVs.
The human genome, considered as a mass, contains more retrovirus sequences than actual genes.
After preclinical studies, a gene therapy trial for SCID - X1 was initiated, based on the use of complementary DNA containing a defective γc Moloney retrovirus — derived vector and ex vivo infection of CD34 + cells.
The more powerful one occurred within a stretch of DNA, or locus, that contains the HCP5 gene, which codes for a human endogenous retrovirus — a genetic fossil of a virus that wove itself into human chromosomes long ago but no longer produces infectious progeny.
Additionally, the originally generated iPS cells contained DNA randomly inserted into the genome from the retrovirus system, although researchers have since made new forms of iPS cells using non-integrating systems and have also improved delivery of the reprogramming factors to the cells.
Every pork cell contains a virus called Porcine Endogenous Retrovirus.