Sentences with phrase «retroviruses infect»

Once in a while, retroviruses infect sperm and egg cells and become «endogenous,» meaning they are passed down from generation to generation.

If the retroviruses infected a person during or after a transplant, they could disrupt important human genes, leading to cancer or other diseases.

Not exact matches

The protein, they found, preferentially binds to human endothelial cells, allowing the retrovirus, which would not normally infect human cells, to enter them.

For the first time, scientists have discovered a pig retrovirus that infects human cells.

These jumping genes behave like retroviruses, except that they never produce the protein coats that allow retroviruses to leave one cell and go to infect another.

He knew that HIV is a retrovirus — the subject of his own heralded research — and that retroviruses don't kill the host cells they infect.

Once a retrovirus has infected an organism, it commandeers that organism's genetic machinery, turning a once - healthy cell into a retroviral powerhouse that spreads the infection to more cells in an irreversible cascade.

Extrapolated to the general population, that meant the recently discovered retrovirus might already have infected at least 10 million still - healthy Americans, each of them innocent of their acquisition of the pathogen.

They searched the fluid for traces of RNA indicating the presence of different classes of retroviruses, RNA viruses that, like HIV, copy their sequence into the genome of infected organisms.

«We were surprised to get a result that suggests that vampire bats may not be the reservoir for this retrovirus but might have been infected independently of monkeys and rats by a yet undiscovered reservoir,» says Marina Escalera, leading author of the study.

Retroviruses, meanwhile, were long thought to infect only animals.

When researchers sequenced the chimpanzee genome in 2005, the biggest difference between it and the human genome was the extinct PtERV1 retrovirus, which inserted its DNA into the cells it infected like HIV does today.

But even if XMRV is not a threat to human health, the fact that a retrovirus that can readily infect human cells was apparently generated by chance in the lab raises some interesting and potentially troubling issues.

A retrovirus that naturally infects many nonhuman primate species can easily jump the species barrier to humans and does so frequently among bushmeat hunters in Africa, according to a study published in the 19 March issue of The Lancet.

Her new genetic analysis studied a few hundred fecal samples collected from Gombe chimps, many of which were infected with SIVcpz, a retrovirus that is HIV's predecessor.

But when retroviruses like HIV infect a cell, they often let the cell live and splice their genes into its DNA.

«The retrovirus we used is replication - deficient and thus can not kill infected cells like other viruses found in the wild,» Chen said.

He was infected with a variant of the retrovirus HTLV - 1 which, unusually, did not cause leukaemia.

«More importantly, a retrovirus can infect only dividing cells such as reactive glial cells, but it does not affect neurons, which makes it ideal for therapeutic use with minimal side effect on normal brain functions.»

Researchers inserted the ADA gene into the cells with the help of a retrovirus, which naturally inserts its genetic material into that of any cell it infects.

We then infected these cells with two retrovirus encoding SOX2 and Ascl1, and you will see sometimes the images depicting the fluorescence, the reporter of fluorescence indicating the expression of the two transcription factors.

HIV - 1 subtype E infected patients with broadened, dual (B / E) V3 loop serology have increased cross-neutralizing antibodies, AIDS Res and Hum Retroviruses, 17:69 - 79, 2001.

Human glioma cells expressing human CD4, infected with an amphotropic retrovirus encoding the cDNA of the CD4 message.

While retroviruses generally only infect dividing cells (because their access to the host genome is thought to rely on the breakdown of the nuclear envelope that occurs in mitosis [Roe et al., 1993]-RRB-, lentiviruses are a genus of the retroviral family that can infect non-dividing cells (possibly through the use of nuclear localization signals by the viral components [Bukrinsky et al., 1992]-RRB-, and thus, offer an advantage when transducing certain cell types that exhibit limited cell division (e.g., neurons).

Rhabdomyosarcoma cells were infected with an amphotropic retrovirus encoding the cDNA of the CD4 message downstream from the MoMLV LTR promoter as well as a neomycin resistance - selectable marker.

A study from Dr. Dusty Miller's laboratory indicates that Jaagsiekte sheep retrovirus (JSRV) infects both sheep and human cells cultured outside the body and does so by attaching to a receptor on the surface of lung cells.

To derive iPS cells from primary NPCs, EGFP - positive NPCs were infected with the retrovirus containing 4 factors.

We can't predict which virus species will slip into eggs and sperm and provide us with the next piece of the human genome, but here is one fact that's pretty unsettling to ponder: If you put a koala retrovirus in a dish with human cells, it can easily infect them.

New retroviruses — such as HIV, which jumped from chimpanzees to humans in the early 1900s — infect our species fairly often.

HIV was identified in the early 1980s as a retrovirus - the class of virus that had been studied in animals, but had only been found to infect humans a short time previously.

On the contrary, recent evidence indicates that XMRV is a contaminant originating from the recombination of two mouse endogenous retroviruses during passaging of a prostate tumor xenograft (CWR22) in mice, generating laboratory - derived cell lines that are XMRV - infected.

In 2011, Paprotka, et al. reported that XMRV likely originated through recombination between 2 endogenous murine retroviruses, PreXMRV - 1 and PreXMRV - 2, during in vivo passaging of the human prostate cancer xenograft CWR - R1, resulting in establishment of the XMRV - infected 22Rv1 cell line [38].

But bioartificial liver support has been used for some years, and there's absolutely no evidence that anyone has been infected with a pig retrovirus.»

Isolation of infected cats using screen or chain link fence barriers is adequate to prevent the transmission of retroviruses.

Feline leukemia virus is a retrovirus that infects cats throughout the world.

Feline immunodeficiency virus (FIV), sometimes called feline AIDS, is a retrovirus that infects cats.

Feline Leukemia virus is a retrovirus because of the way it behaves within infected cells.

There are multiple retroviruses that can infect cats.

Because retroviruses can be spread «vertically» (from mother to offspring) kittens can be infected very early.