Sentences with phrase «retroviruses insert»

Some researchers are starting to show interest in using the technique to explore what happens when retroviruses insert their DNA into the genome of a host.

Not exact matches

In 2006, he used retroviruses to insert four genes into the chromosomes of mouse skin cells.

Lee's team used a retrovirus to transfer the fluorescent gene to dog fibroblast cells, but they could not control where the virus inserted the gene.

In one such study by Ronald Evans and colleagues, the gene for rat growth hormone is stably inserted into mouse cells by a retrovirus.

Before Katlyn showed up at NIH, the doctors there were already well prepared: They had inserted healthy human ADA genes into a modified mouse retrovirus — a type of virus that can enter human cells and transfer new genetic material right into the DNA strands in their nuclei.

Biologists have adapted retroviruses to insert beneficial genes into the genome, rather than their own DNA.

Then De Luca and colleagues used a retrovirus to insert a healthy copy of the LAMB3 gene into DNA in the lab - grown skin stem cells.

Other researchers have long been concerned that using a retrovirus to insert genes at random points in cells» genomes might cause cancer.

When researchers sequenced the chimpanzee genome in 2005, the biggest difference between it and the human genome was the extinct PtERV1 retrovirus, which inserted its DNA into the cells it infected like HIV does today.

The theory: Millions of years ago, an ancient human ancestor contracted a retrovirus that inserted its DNA into the host's reproductive germ cells, passing the viral DNA down the ancestral line.

Retroviruses go one step further and insert it directly into our DNA.

Another difficulty is that the gene that codes for dystrophin is too large to fit into the retroviruses that scientists use to insert genes into cells.

Researchers inserted the ADA gene into the cells with the help of a retrovirus, which naturally inserts its genetic material into that of any cell it infects.

By the beginning of the 1990s, researchers were just beginning to understand retroviruses — those like HIV that reproduce by inserting their DNA into a host's genome.

Drawing upon the cell culture expertise of Noriyoshi Sakai, Ph.D., and Kayoko Kurita, of Fukui Prefectural University, the Japanese - U.S. team developed a system that enables immature sperm cells, or spermatagonia, taken from male zebrafish to survive long enough in vitro that they can receive foreign genes inserted by a retrovirus.

Additionally, the originally generated iPS cells contained DNA randomly inserted into the genome from the retrovirus system, although researchers have since made new forms of iPS cells using non-integrating systems and have also improved delivery of the reprogramming factors to the cells.

A retrovirus spreads by inserting something called an enzyme into healthy cells.