Sentences with phrase «reveal cellular heterogeneity»
Our results reveal cellular heterogeneity in the onset of HSC aging and implicate a role for JAK2V617F - driven proliferation in the p53 - mediated functional decline of old HSCs.
http://www.sanger.ac.uk/ Not exact matches
In conclusion, this new study identifies the cellular origin of Pik3ca - induced tumours and reveals that oncogenic Pik3ca activates a multipotent genetic program, setting the stage for future intratumoural heterogeneity at the earliest stage of tumor development.