Not exact matches
In conclusion, this new study identifies the cellular origin of Pik3ca - induced tumours and
reveals that oncogenic Pik3ca activates a multipotent genetic program, setting the stage for future intratumoural heterogeneity at the earliest stage of
tumor development.
While these mutations do not directly relate to the
development or progression of a
tumor, they can
reveal its lineage — how individual
tumor cells are related to each other.
Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna
reveal a surprising role for histone deacetylase 1 (HDAC1)-- a member of a family of chromatin modifying proteins — in the
development of skin
tumors.
A new study from the German Cancer Research Center has
revealed that the entire species of Marmorkrebs originate from a single mother crayfish, in a clonal reproduction that may help shed new light on processes in
tumor development.
Combining this with various cancer models will
reveal when and where certain levels of chromosome segregation errors impact organismal health and
tumor development.
In his project, Dr. Li is investigating whether beta blockers target T cells to control breast
tumor development, and is also working to understand how this pathway regulates T cell responses to
tumors, which may
reveal novel targets for the immunotherapy of breast cancer.
However, some studies have
revealed that the presence of tannins (though minimal) may contribute to the
development of
tumors, if consumed in high concentrations.