Sentences with phrase «reversal of cognitive impairment»
We report here a reversal of cognitive impairment in aged huAPP / PS1 mice by J147 and provide evidence that these beneficial effects are due to the ability of J147 to normalize several different aspects of AD pathology, likely through the up - regulation of the neurotrophin pathway.
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The available data suggest that reversal of scopolamine - induced cognitive impairment is a viable model for predicting pharmacodynamic signals of cognition enhancing compounds in animals [91].
His group has developed a new approach to the treatment of Alzheimer's disease, and this approach has led to the discovery of subtypes of Alzheimer's disease, followed by the first description of reversal of symptoms in patients with mild cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal of Cognitive Decline) preversal of symptoms in patients with mild cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal of Cognitive Decline) cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal of Cognitive Decline) pReversal of Cognitive Decline) Cognitive Decline) protocol.