Various nutritional factors found in whole food diets have been found to assist
in reverse cholesterol transport (including phospholipids, CLA, and polyphenols).
We conclude that apolipoprotein E does not function to remove cholesterol from macrophages but rather to participate in «
reverse cholesterol transport.»
Reverse cholesterol transport, the process by which HDL removes cholesterol from plaque in the arteries and transports it to the liver where it is used to produce hormonal compounds or eliminated from the body.
Research Interests: lipid metabolism; lipoprotein metabolism; atherosclerosis; obesity; diabetes;
reverse cholesterol transport; triacylglycerol; nutrition
Research Interests: Atherosclerosis; HDL metabolism; Atrial fibrillation; Genetics; Genomics; eQTL; Gene expression;
Reverse cholesterol transport; Dysfunctional HDL; RNAseq; Allelic expression imbalance; ABCA1; Mouse models; Zinc finger nuclease
Research Interests: cholesteryl ester transfer protein; lipid transfer inhibitor protein; apolipoprotein F;
reverse cholesterol transport; LDL; HDL; lipid transport; triglyceride; lipid droplets; fat storage
An effect of walnuts on ex vivo cholesterol efflux was observed with whole serum but not apoB - depleted serum; in addition to HDL, LDL can serve as an acceptor of free cholesterol in
the reverse cholesterol transport pathway (39), indicating that walnuts may have a greater effect on global cholesterol efflux than HDL - specific efflux.