Sentences with phrase «reversed by an antibody»
This sensitivity was reversed by an antibody known to neutralise the molecule.
https://www.newscientist.com/ Not exact matches
They found that blocking ANGPTL3 activity with an investigative injectable antibody, known as evinacumab, reduced triglycerides by up to 76 percent and lowered LDL cholesterol 23 percent in human study participants, and largely reversed signs of atherosclerosis in a mouse models.
The research, published in the September issue of Immunity, is part of a broad reverse - engineering effort by scientists around the world to use antibodies isolated from HIV - infected people to guide the development of a successful vaccine.
Infected mice were already showing measurable weight loss that was reversed by administration of the antibody, demonstrating therapeutic potential even after the onset of disease.
The researchers plan to intensively study the immune responses generated by therapeutic vaccines, broadly neutralizing antibodies, and latency reversing agents in both acutely infected individuals and also in preclinical studies.
BIIB054 was originally developed by biotech company Neurimmune, using a platform they call Reverse Translational Medicine (RTM ®), which derives therapeutic antibody candidates from libraries of de-identified B - cells isolated from ostensibly healthy older adults (those free of specific neurological diseases of aging).