Sentences with phrase «reversible local folding»

A reversible local folding step in which a duplex docks and undocks from the ribozyme core was observed directly in single - molecule time trajectories, allowing the determination of the rate constants and characterization of the transition state.

Not exact matches

A 1 - millisecond simulation of the folded protein BPTI reveals a small number of structurally distinct conformational states whose reversible interconversion is slower than local relaxations within those states by a factor of more than 1000.