Umbrella reviews systematically search, organise, and evaluate existing evidence from multiple systematic reviews and / or meta - analyses on all health outcomes associated with a particular exposure.11 We conducted
a review of coffee consumption and multiple health outcomes by systematically searching for meta - analyses in which coffee consumption was all or part of the exposure of interest or where coffee consumption had been part of a subgroup analysis.
Not exact matches
Nehlig A, Debry G. Consequences on the newborn
of chronic maternal
consumption of coffee during gestation and lactation: a
review.
Introduction While a large body
of research has
reviewed the physiological effects
of coffee consumption, only few studies have considered the potential relationships between
coffee consumption, mood and emotion.
Moderate
coffee consumption is typically defined as 3 - 5 cups per day, based on the European Food Safety Authority's
review of caffeine safety18.
In various systematic
reviews of epidemiological studies, regular caffeine or
coffee consumption was associated with a lower risk
of diabetes type 2 [70,159,182,191] but, according to one study, only in individuals who had previously lost weight [206].
Data
reviewed by IARC also suggests that there is no association between
coffee consumption and increased risk
of pancreatic cancer31.
These antioxidant and anti-inflammatory effects are also likely to be responsible for the mechanism behind the beneficial associations between
coffee consumption and liver fibrosis, cirrhosis, and liver cancer110 that our umbrella
review found had the greatest magnitude
of effect compared with other outcomes.
Fig 1 Flowchart
of selection
of studies for inclusion in umbrella
review on
coffee consumption and health