To explore a potential link between the outbreak and associated illness in humans, we blindly tested available sera from titi monkeys (n = 59),
rhesus macaques housed in the same building (n = 36), CNPRC personnel and close contacts (n = 20), and random human blood donors (n = 81) for evidence of recent or prior infection by TMAdV by virus neutralization (Fig. 6).
In addition, we checked for TMAdV in rectal swab samples from
rhesus macaques housed in the same building as the titi monkeys (n = 26) and in pooled droppings from wild rodents (n = 2) living near the titi monkey cages.
Not exact matches
Interestingly, none of the 133
rhesus macaques (Macaca mulatta)
housed in the same building became sick during the outbreak, and neither did any of the Old World monkeys from surrounding outdoor colonies of
rhesus and cynomolgus
macaques (Macaca fascicularis).
Whole blood from
rhesus macaques (Macaca mulatta)
housed at the Tulane National Primate Research Center was used for CD4 + T cell isolation and ZFN treatment.