Sentences with phrase «rhodopsin as»
Although the location of carazolol in the β2 - adrenergic receptor is very similar to that of retinal in rhodopsin, structural differences in the ligand - binding site and other regions highlight the challenges in using rhodopsin as a template model for this large receptor family.
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In this study, the team worked on a rhodopsin from a marine bacterium, which normally pumps sodium, as well as lithium, across the cell membrane.
This work focused on rhodopsins, which are light - activated molecules found in the human eye as well as in bacteria.
Currently, we use Rosetta in conjunction with EPR distance and mobility measurements in order to model the rhodopsin / G - protein complex and conformational changes occurring as the G - protein binds to rhodopsin.
C - X-C chemokine receptor type 4 (CXCR4), also known as fusin or cluster of differentiation 184 (CD184), is a seven transmembrane (TM) G - protein coupled receptor (GPCR) belonging to Class I GPCR or rhodopsin - like GPCR family [1, 2].
Crystal structures exist for the G - protein, as well as activated rhodopsin bound to the C - terminal tail of Galpha, but not for the rhodopsin / G - protein complex.
She wanted to connect chemistry to biology in some concrete way, so she'd planned to join a biochemistry lab focused synthesizing retinal (vitamin A) as a way to understand rhodopsin proteins.
Importantly, akin to HESC - RPE in vivo, cells at the outside edge of the iPS - RPE cell bolus could phagocytose photoreceptor outer segments from the RCS rat, as indicated by the presence of rhodopsin - positive photoreceptor material within the cellular membrane of iPS - RPE labelled with HSM (Fig. 5E).
Along these lines I have heard that there is a bacteriophage (virus that infects bacteria) that will substitute its own rhodopsin gene — which it has no use for in the absence of a host — for the bacterial rhodopsin so that the bacterium will continue to produce energy even as its systems shut down due the the infection.