Sentences with phrase «ribosome biogenesis»
"Ribosome biogenesis" refers to the process through which ribosomes, which are tiny cellular structures responsible for protein synthesis, are created and assembled in a cell. It involves different steps and components coming together to form functional ribosomes that can carry out their important role in making proteins. Full definition
This study reveals a new function for Hfq in ribosome biogenesis with implications for translational control.
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Next they tested an additional 27 genes that are known to be involved in various steps of ribosome biogenesis to verify whether SSUP was required for ESC maintenance.
An unexpected ribosome biogenesis role expands the post ‐ transcriptional gene expression functions of a key bacterial RNA chaperone beyond binding / regulation of small RNAs.
Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus.
The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double - edged sword.
The synthesis of eukaryotic ribosomal subunits requires the concerted activity of ~ 200 assembly factors that drive ribosome biogenesis through a series of pre-rRNA cleavage, folding and modification reactions, which are coupled to the incorporation of ribosomal proteins (Henras et al., 2015; Woolford and Baserga, 2013; Zemp and Kutay, 2007).
The synthesis of rRNA is the rate - limiting step in ribosome biogenesis.
It is well known that ribosome biogenesis is a key component of the cell cycle as it regulates cell size and growth and the IBS team has uncovered that SSUPs play a critical role in maintaining induced pluripotent stem cell integrity.
A protein domain that is found in many RNA - binding proteins that are required for mRNA synthesis, pre-mRNA splicing, ribosome biogenesis and RNA decay.
NOP2 and PPRC1 are involved in ribosomal biogenesis and are coexpressed with DKC1, a gene involved in ribosome biogenesis and also a component of the telomerase ribonucleoprotein enzyme complex.
mTOR - raptor complex (composed of mTOR, raptor, and GβL) is sensitive to rapamycin and regulates cell growth, in part, by phosphorylation of the ribosomal protein S6 (rpS6) kinase (p70S6K or S6K1) and subsequent phosphorylation of rpS6 to stimulate protein translation and ribosome biogenesis (9, 10).