Sentences with phrase «ribosome entry»
However, some bicistronic vectors take advantage of an element called an Internal Ribosome Entry Site (IRES) to allow for initiation of translation from an internal region of the mRNA.
http://blog.addgene.org/
hnRNP A1 is a multifunctional RNA binding protein which is involved in pre-mRNA splicing, export of mature transcripts from the nucleus, mRNA turnover, and internal ribosome entry site (IRES)- mediated translation.
A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt - flanked neo cassette into the 3» untranslated region (after the translational termination site) of the glutamic acid decarboxylase 2 locus (Gad2) on chromosome 2.
The liver cells transfected with an HCV internal ribosome entry site (IRES)- driven luciferase reporter that were treated with SBEL1 reduced reporter activity by 50 % compared to control.
Not exact matches
We present a cryo — electron microscopy study at ∼ 13 to 15 angstroms of the entry of tmRNA into the ribosome.
A segment of the 5» nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation.