Not exact matches
The ability of RNA to orchestrate large - scale conformational changes may
help explain why the
ribosome and the spliceosome are RNA - based machines.
Roughly half of all antibiotics attack pathogens»
ribosomes, so understanding how the drugs fit into and disturb
ribosomes» proper functioning could enable the discovery of new antibiotics to
help stem the tide of rising antibiotic resistant strains.
The following year, Frank prepared
ribosomes, cellular structures that
help make proteins, using the cryo - EM method.
Ribosomes decipher the sequence of an mRNA with the
help of small cloverleaf shaped molecules called «transfer» or tRNA.
Among the key elements engineers need to get an organism such as E. coli to make a protein from a synthesized gene are extra sequences such as promoters (to
help the cell make RNA from DNA) and
ribosome binding sites (or RBS, which the cell needs to make proteins from the RNA).
LOS1
helps relocate transfer RNA (tRNA), which bring amino acids to
ribosomes to build proteins.
Now, John Chaput and his colleagues at Arizona State University's Biodesign Institute have produced the first genome - wide investigation of cap - independent translation, identifying thousands of mRNA sequences that act as Translation Enhancing Elements (TEEs), which are RNA sequences upstream of the coding region that
help recruit the
ribosome to the translation start site.
A
ribosome is
helped by ATP, which powers it as it walks along the messenger RNA and as it stitches the amino acids together.
Messenger ribonucleic acid (mRNA) is the form of RNA that
helps transfer genetic information from inside the cell nucleus to
ribosomes in the cytoplasm.
Wolin and her colleagues had begun to answer questions about Ro's function when their earlier experiments demonstrated that the Ro protein binds to small RNA molecules that are misfolded versions of those that
help make up the cell's
ribosomes, which are its protein assembly lines.
Just like a chef sometimes has the
help of an assistant chef when making his cuisine,
ribosomes sometimes get a little bit of
help making proteins.