Sentences with phrase «ribosomes into»

These units, which contain detailed instructions for the synthesis of specific proteins, are then read and translated by ribosomes into proteins.

This leads to degradation of «viral» RNA, preventing its translation on ribosomes into a protein encoded by it, thereby reducing the viral gene expression,» says one of the main co-authors of the research Alexander Timin, a JRF of the Novel Dosage Laboratory at Tomsk RASA Center.

But when we put this restored ribosome into the original sensitive bugs, they get even more screwed up.»

During this crucial step, messenger RNA (mRNA), which is a RNA copy of a gene's recipe for a protein, is translated by the cell's ribosome into the sequence of amino acids that will make up a newly synthesized protein.

Not exact matches

A ribosome forms itself (we know not how), and even after being separated into its protein components in various chemicals, will jump back into working shape again when the chemicals are removed.

Ban chose to work on one of the most difficult problems in structural biology: imaging the active site of the ribosome, a site within the large subunit of the ribosome where the bonding of individual amino acids into a protein chain is catalyzed.

DNA is transcribed into messenger RNA (mRNA) that carries the code to ribosomes, the molecular machines that build proteins by reading the mRNA instructions.

And with many large, complicated molecules found in and around cells — uch as ribosomes, which turn genetic instructions into working proteins — scientists simply could not make that happen.

Noller (p. 1508) discusses how the basic building block of RNA — the double helix — has been fashioned into the intricate «protein - like» three - dimensional surfaces of the ribosome.

Roughly half of all antibiotics attack pathogens» ribosomes, so understanding how the drugs fit into and disturb ribosomes» proper functioning could enable the discovery of new antibiotics to help stem the tide of rising antibiotic resistant strains.

Ramakrishnan further revealed that the ribosome ensures accuracy not only by monitoring the stability of the bonds between amino acids that the ribosome stitches together into proteins but also by using a ruler to check the geometry of the bonds.

When prompted, the tRNA synthetase charges a tRNA with the bio-orthogonal amino acid, which is then used by ribosomes to insert the tag into proteins made in the cell.

It works by isolating the protein - making machines of cells (called ribosomes), which turn mRNA copies of DNA (genes) into proteins.

For most known genes this «messenger» or mRNA is then shuttled off to a ribosome of a cell where its translation into a protein sequence occurs.

A single mRNA typically has several ribosomes traveling along it, all simultaneously translating this transcript into protein.

They then separated the cells into two groups — those containing mRNAs associated with ribosomes on the endoplasmic reticulum, and those containing mRNAs associated with free - floating ribosomes in the neighboring fluid - filled space known as the cytosol.

These other mutations pull the ribosome back into pretty good shape.

Erythromycin targets bacterial ribosomes — the nanomachine responsible for the translation of messenger RNA (mRNA) sequences into protein — thus preventing synthesis of the proteins required for continued growth and survival.

Crystal structures of the ribosome bound to elongation factors provide insights into translocation and decoding.

Ribosomes, which are themselves made up of many proteins and RNAs, read genetic instructions copied from DNA into messenger RNAs.

RNA serves as the template for translation of genes into proteins, transferring amino acids to the ribosome to form proteins, and also translating the transcript into proteins.

This typical, casual canteen chat only partly reveals the facility's successful lab culture, which encouraged Ramakrishnan to focus on understanding the ribosome, the cellular machinery that turns RNA into protein.

Ribosomes are the molecular machines responsible for the translation of mRNA sequences into the amino - acid sequences of the specified newly synthesized protein.

In an era of free love and violent protests, about 100 people danced on the grass, enacting one of the greatest discoveries of the century: how the ribosome translates genes from DNA into proteins.

«You'll see that the guy goes into the middle of the ribosome, and suddenly up comes a puff of smoke,» says Berg.

The instructions for the synthesis of proteins are stored in the DNA in the cell nucleus, are first «transcribed» into mRNAs, and exported from the nucleus to the ribosomes in the cell cytoplasm.

Investigations of how short chains of nucleic acids replicate themselves in vitro have even provided clues to primitive genetic codes for translating nucleic acid information into protein information, systems that could have preceded the elaborate machinery of ribosomes and activating enzymes with which cells now manufacture protein.

This step is when the ribosome machinery, which reads the RNA genetic code and converts it into an amino acid protein chain, attaches onto the start of the RNA transcript.

This unusual shape prevents ribosomes — the button - shaped organelle that zips along the messenger RNA and strings together amino acids into proteins — from binding to the appropriate piece of RNA.

To show its promise, Zhang's team inserted C2c2 into E. coli bacteria, where it silenced a gene by cutting up a form of RNA that carries the gene's information to the ribosomes.

We present a cryo — electron microscopy study at ∼ 13 to 15 angstroms of the entry of tmRNA into the ribosome.

One of the winners of this year's Nobel Prize in Chemistry describes the efforts that went into piercing the ribosome's secrets

This process takes place inside veritable macromolecular machines known as ribosomes, and starts by transcribing genetic information from a cell's DNA into transportable units known as messenger RNAs (mRNAs).

As a result, these mRNA molecules — stripped of their green fluorescent proteins, bound to ribosomes, and ready to be translated into a protein — appear red.

Each of the twenty - one amino acids used by the human body has a tRNA binding partner that carries it to the ribosome where it can be incorporated at the appropriate point into a growing protein.

A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt - flanked neo cassette into the 3» untranslated region (after the translational termination site) of the glutamic acid decarboxylase 2 locus (Gad2) on chromosome 2.

As the ribosome moves down to the next codon, the correct tRNA molecule, complete with the correct amino acid, moves into place.

The researchers were also able to show that the process of translating certain sections of genetic information into new proteins is impaired in these ribosomes.

Her starting point is that many antibiotics target bacteria's» ribosomes, «the universal cellular machines that translate the genetic code into proteins.»

Julia is also recognized for her role as a technology innovator in plant biology; her development of the «translating ribosome affinity purification «TRAP» method has opened a window into the «translatome».

The helper complex lets the ribosome translate genetic messages into protein more quickly than the ribosome could on its own.

As expected, they found that the normal and extra-long genetic instructions were both translated into huntingtin proteins when they met up with a ribosome (the chef from our analogy above).

Andrei Korostelev of the University of Massachusetts Medical School focuses on capturing minute structural changes in ribosomes as they translate RNA into proteins.

Ribosome the large molecular complex «machines» that translate the mRNA code into the amino acid chain that form proteins.

Here we report the in vivo transcription of DNA containing dNaM and dTPT3 into mRNAs with two different unnatural codons and tRNAs with cognate unnatural anticodons, and their efficient decoding at the ribosome to direct the site - specific incorporation of natural or non-canonical amino acids into superfolder green fluorescent protein.

The ribosome, while not technically an enzyme, is the most important catalyst for stitching together amino acids into proteins.

The potent toxin ricin3 is made from a protein in the castor seeds that, if ingested (orally, nasally, or injected), gets into the ribosomes of your cells where it prevents protein synthesis, which kills the cells.