Sentences with phrase «right dynein»
Indeed, the group found that the affected gene, named left - right dynein (lrd), comes on in the «node» — a key source of patterning signals — just before the appearance in the mouse embryo of the first known left - right asymmetries, the left - sided expression of two genes called nodal and lefty.
http://www.sciencemag.org/ Not exact matches
The stiffest regions of dynein (yellow, on left) are the sites where ATP binds to the protein and releases energy when converted into ADP (colored, on right).
«It's long been my hunch that the earliest events in left - right asymmetry involve a shunting [of signaling proteins such as ZIC3] to one side or the other, and it's certainly appealing to invoke dyneins and the cytoskeleton to help with that,» says Casey.
That suggests that the dynein's job could be either to drag molecular signals that activate lefty or nodal to the node's left side, or to carry signals that repress them to the right side, says Joseph Yost, a developmental biologist at the University of Utah in Salt Lake City.