Sentences with phrase «risk amount over time»

If you're withdrawing profits every month then you would not keep increasing your risk amount over time.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

As a result, one would expect that the amount of «risk adjustment» to increase not decline over time.

Fidelity believes one of the best ways to do that over the long term is by considering an appropriate amount to invest in a diversified portfolio of stock mutual funds, exchange - traded funds (ETFs), or individual stocks as you plan and implement an investment strategy that fits your time horizon, risk preferences, and financial circumstances.

If the speculative bubbles and crashes across market history have taught us anything (particularly the repeated episodes of recklessness we've observed over the past two decades), it's this: regardless of the level of valuation at any point in time, we have to allow for the potential for investors to adopt a psychological preference toward risk - seeking speculation, and no amount of reason will dissuade them even when that speculation has already made a collapse inevitable over a longer horizon.

Because the purpose of a bond ladder is to provide predictable income over a long period of time, taking excessive amounts of credit risk probably doesn't make sense.

And then lastly, we feel great about the amount of cash that this business continues to kick off, allowing us to reinvest in this low risk, high return new unit growth and the infrastructure to support it, while continuing to pay a competitive and over time, growing dividend, as well as consistent, robust share repurchases.

They add: «The greatest reduction in risk of developing metabolic risk factor clustering observed for intermediate levels of physical activity and leisure time sitting was unexpected and suggests that moderate amounts of both moderate - to - vigorous physical activity and leisure time sitting may be sufficient to protect against developing metabolic risk factor clustering over time... The lack of protection for the most active adults may reflect a chance finding, or confounding by other factors such as wider use of prescription drugs by participants in less active groups.

In another finding, female scoliosis patients received two times more X-rays than non-surgical patients, amounting to twice the radiation exposure to the breasts, ovaries and bone marrow, and correlating to an over two percent increased lifetime risk of fatal breast cancer, almost one percent risk of fatal leukemia, and three percent risk of genetic defects.

Past epidemiological studies have found a link between the amount of time spent cooking over woks and the risk of lung cancer.

Children's developing brains and nervous systems are susceptible to toxins and even small amounts of lead exposure add up over time, increasing risk of developmental effects.

However, receiving higher amounts of calcium over a long period of time raises the risk of kidney stones in some people.

Now here's the thing, there are many ways to multiply that return many times over — you can go on margin with your investments, but it's something that takes a tremendous amount of risk, which to me, boils down to making a gamble.

Over time, after learning the approach and screen time, a trader will start to develop their own unique style and entry methodologies to extract as much profit from the market whilst risking the least amount possible.

From a psychological perspective, though, especially for an amount of money this big, he says it may be better to take an annual payment over time (that'll still be millions per year) rather than having to manage all that money at once and risk being another sad lotto winner.

Instead, understand that if you maintain a consistent risk amount that you're comfortable with, and only trade high - probability price action strategies, over a series of trades you should come out profitable, even if you lose the majority of the time.

Fidelity believes one of the best ways to do that over the long term is by considering an appropriate amount to invest in a diversified portfolio of stock mutual funds, exchange - traded funds (ETFs), or individual stocks as you plan and implement an investment strategy that fits your time horizon, risk preferences, and financial circumstances.

Investing small amounts systematically in the age - based portfolio, going forward, gives the portfolio as a whole more risk introduced, but slowly over time.

This will improve your score over time, because people owing smaller amounts on their credit accounts are viewed as having a lower repayment risk than those who owe more.

To alleviate some of the risks with investing large lump sum investments, the amount can be divided into smaller sums and invested at regular intervals over a period of time

Risking a small amount per trade and gaining a small amount of pips consistently over time can make you rich quicker than you may realize.

The risk - adjusted age - based investment tracks allow investors to choose different amounts of anticipated risk and different planned changes in risk over time.

The object of investment strategies is to maximize our real rate of return subject to the amount of risk we are able or willing to take over a given time period.

Over time, this profit is based mainly on the amount of risk associated with the investment.

First that you have misjudged the chronology on how the IPCC formed, second, echoed by many, that it was too broad brushed (von Storch and Kloor), it doesn't take into account how the IPCC bureaucracy has turned over several times over the years (Eli Rabbet), you've never provided proof as to how the IPCC's control extends out into the academic realm, and it completely overlooks all the other possibilities, ie, the strength of the science is robust and the risk dire enough to receive to the amount of funding, attention, etc. and any other option at the time would have been outrageous, especially considering that what has been predicted is currently happening.

Additionally, it builds cash value that reduces the net amount at risk to the insurance company, thereby reducing the total costs associated with providing insurance over time.

With sufficient funding the amount at risk will reduce enough over time, and growing cash value account will pay enough interest to compensate for the rising cost of insurance.

A major drawback to blended life insurance is the risk that the premium, or the amount you pay for the policy, will increase over time.

Aboriginal Australians make up 3 % of the Australian population and have a life expectancy over 10 years less than that of non-Aboriginal Australians.3 The small amount of evidence available suggests that Australian Aboriginal children and adolescents experience higher levels of mental health - related harm than other young people4, 5 including suicide rates that are several times higher than that of non-Aboriginal Australian youth.4, 6 These high levels of harm are linked to greater exposure to many of the known risk factors for poor mental health and to the pervasive trauma and grief, which continues to be experienced by Aboriginal peoples due to the legacy of colonisation.7, 8 Loss of land and culture has played a major role in the high rates of premature mortality, incarceration and family separations currently experienced by Aboriginal peoples.

For this to work many repetitions are required over a period of time and after risking massive amounts of cash the results are often inconsistent.

However, the level of our investment represents «a toe in the water» approach as we have put relatively small amounts of capital at risk as we learn the market and determine the capacity to invest more and grow over time.