Sentences with phrase «risk disease»

Although the number of prostate needle biopsies (PNB) has been reduced, patients who undergo PNB are significantly more likely to be diagnosed with high risk disease, and detection of intermediate risk, potentially curable PCa has likely decreased.

Management of low risk prostate cancer with AS appears feasible and safe, yet most men in the U.S. with low risk disease still undergo definitive therapies such as radical prostatectomy, which carry the burden of urinary, bowel, and sexual dysfunction that can be avoided, or at the very least postponed, with management on AS.

Significant anti-tumor activity was observed as well: nearly 70 percent had a near complete or complete response within three months post treatment, which compares favorably with the expected responses (less than 40 percent) in patients without high - risk disease following an ASCT.

Some side effects can be so debilitating that patients decide to quit therapy and risk disease recurrence or progression.

Compared with a historical control trial, AIDA 0493, which used a significantly higher anthracycline dose and did not include ATO consolidation, the event - free survival for patients with standard - risk disease in this trial was noninferior.

Patients were stratified as having standard - risk or high - risk disease based on white blood cell count.

Finally, the relapse risk for patients from the end of consolidation 1 was only 4 % at 3 years and was not significantly different between standard - risk and high - risk disease patients.

Major Health Problems: Examples of high risk diseases or health conditions include Alzheimer's, cancer, diabetes, epilepsy, HIV, multiple sclerosis, and pancreatic disease.

In addition, Haymart says conversations about limiting surgery for those with low - risk disease may be appropriate.

Patients with intermediate - risk disease had a 3.75 times higher chance of dying of prostate cancer compared to patients with low - risk disease (11.5 percent vs. 3.7 percent at 15 years, respectively).

All had abnormalities of TP53 or ATM — two mutations associated with high - risk disease — and two patients had increasing BTK C481S clones, also a high - risk marker.

Thus, the key concern is not only the increased risk of being diagnosed with high risk disease, but, more importantly, the missed opportunity to offer curative intervention for patients with intermediate risk PCa.»

Compared to patients with low - risk disease, those with intermediate - risk cancer (PSA > 10ng / ml or Gleason score 7 or clinical stage T2b / 2c) had a nearly four-fold higher chance of dying from prostate cancer within 15 years.

«Importantly, this was true among men with low - risk disease, for whom active surveillance may be a clinically viable option and side effects of surgery might be avoided.»

The majority of study participants had either low - or intermediate - risk disease, and were more likely to have been treated with surgery, followed by radiation and active surveillance.

Ten of the 12 patients demonstrated high - risk disease or relapse in disease prior to study participation.

But among those who are diagnosed, only 8 percent fewer are getting initial surgery or radiation treatments — even as data shows those with low - risk disease can substitute surveillance.

Watchful waiting or active surveillance — which involve monitoring patients without delivering treatment — are options, especially for those patients with low - risk disease or limited life expectancy.

The majority of men diagnosed with prostate cancer have low risk disease and face a difficult decision between having the disease managed conservatively through AS or undergoing definitive therapy.

«Many researchers have been advocating for active surveillance for men with low - risk disease,» he said.

An unusual observation by Hopkins scientists about how testosterone affects prostate cancer cells may lead to more effective radiation therapy in men with high - risk disease.

Patients with standard - risk disease had significantly better overall survival (98 % vs 86 %; P =.003) and event - free survival (95 % vs 83 %; P =.03) compared with high - risk disease.

Choosing no treatment and regular check - ups didn't seem to stress men with low - risk disease, study found

The main issue is whether this is an early sign that more high - risk disease, more disease that has spread and more deaths from prostate cancer will happen, he added.

In 2006, he founded the Dwayne Johnson Rock Foundation, meant for helping the children with at - risk diseases and the terminally ill.

Most men with prostate cancer have low - risk disease and must make the difficult decision between having their cancer monitored or receiving treatment.

In an era when long - distance travel was difficult and exhausting even when the trains ran on time, the weather was fair, and the roads weren't thick rivers of mud, Julia — and her four young children, who often accompanied her — risked disease, death and capture whenever they journeyed between home and headquarters.

The new pup and your resident pets should have no direct contact, not even sniffing through the screen or beneath the door, as even this risks disease transmission.

«Properly administered vaccines help reduce the risk of infection, so we encourage horse owners to work with their veterinarian to formulate a complete vaccination program addressing the core and risk diseases,» said Zoetis Technical Services Veterinarian Kevin Hankins, DVM, MBA.

Rabies vaccination of dogs is generally governed by law because of the risk the disease poses to humans.

Do nt be scared away by horror stories about countless shots in the stomach the current procedure is much less unpleasant than it used to be, and is certainly preferable to risking the disease.

A person who will test positive for high - risk diseases may possibly have higher premium plans rather than another healthy individual who will not show any signs of medical issues.