Sentences with phrase «risk factor exposures»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Alcohol is not the only important factor to consider when trying to reduce your cancer risk — your genes, exercise regimen, and exposure to pollutants can play a role, too.

Targets exposure to historically rewarded factors in fixed income securities to help seek better risk - adjusted returns

There can be no assurance that performance will be enhanced or risk will be reduced for funds that seek to provide exposure to certain quantitative investment characteristics («factors»).

However investors may want to maximize their exposure to the underlying factors while still maintaining a market - like risk profile.

Portfolio managers selecting bonds from this grouping can gain access to the same risk factor without needing to buy all the bonds in the index to get the beta exposure.

The ideal portfolio optimization algorithm perfectly balances trading costs, instruments, asset classes, factor exposure (but only when needed), strategies, and does it all under constraints imposed by risk management.

EM portfolio exposure contributes to risk factor diversification, viz - a-viz inflation related to commodities and China.

In an ongoing series of white papers, which started with «Finding Value: Understanding Factor Investing,» MSCI Research is exploring factors that identify specific risk exposures with the potential for an accompanying premium.

The product is derived from Morningstar's Global Risk Model, released in 2016, which tracks portfolio risk by monitoring each stock's underlying economic exposure to 36 factRisk Model, released in 2016, which tracks portfolio risk by monitoring each stock's underlying economic exposure to 36 factrisk by monitoring each stock's underlying economic exposure to 36 factors.

None of the factors consistently generated positive performance during recent market crashes However, almost any factor exposure would have increased the risk - return ratio of an equity - centric portfolio Low Volatility and Mean - Reversion would have been most beneficial, Momentum least INTRODUCTION A

Factor exposure should be considered a source of returns as well as of risk Factor biases can be measured top - down or bottom - up The results of the two approaches do not necessarily reconcile INTRODUCTION Factor investing has become immensely popular in recent years and assets in smart beta products

SUMMARY Some factors show structural sector exposure while others rotate sectors frequently Sector concentrations explain factor performance and may represent concentration risks Value is currently long Financials, Low Volatility is short Health Care, and Growth is short Energy INTRODUCTION Despite

Instead of the weights of different types of bonds, investors can hone in on exposure to factors that drive portfolio performance, such as interest rate risk, credit risk, and others.

By systematically and deliberately setting exposure factors such as momentum, quality, or value, managers can utilize smart beta strategies to improve returns, reduce risk or enhance diversification.

Where we are concerned about volatility risks in global equity, we can focus exposure on stocks that exhibit the «quality» factor.

If anything, the first few weeks of the year have served as a valuable reminder that investing in public markets is inherently volatile and that our main defense against that volatility is to diversify our risk exposures by owning a variety of asset classes and risk factors.

Exposure to secondhand smoke, both as a developing fetus and after birth, is a significant risk factor for SIDS.

He described the goal of reducing the overall number of head impacts that high school football players sustain in a season as «logical» and «appealing,» but noted that, «until the risk factors for chronic traumatic encephalopathy [25](CTE) are better defined by carefully designed and controlled research,» and research determines «what the advisable limit to head impact exposure should be,» employing contact limits or establishing «hit counts [4]» will remain «educated guesses, at best.»

Indeed, a long duration of breastfeeding (> 7 months) has been associated with a reduced risk of overweight and obesity, 2 while a short duration (≤ 4 months) may not be sufficient to obtain the beneficial effects of breastfeeding.3 Another confounding factor is early exposure to antibiotics, which is increasing even for minor infections.

Depending upon where you live and how dark your skin is, going outside regularly may be all that is required for you or your baby to generate adequate amounts of vitamin D. However, one of the problems with getting your vitamin D with sun exposure is simply that it's hard to determine how much time outside is needed since it depends on so many factors (skin tone, latitude, time of year, how much skin is exposed, amount of air pollution, etc.) Keep in mind that there is also a concern of sunburn and increased risk of skin cancer with too much sun exposure.

While smoking remains the biggest risk factor for COPD, the study demonstrates that childhood illnesses (such as asthma, bronchitis, pneumonia, allergic rhinitis, eczema) and exposures to parental smoking are also linked to the disease.

Healthcare providers may screen a child more frequently if there are additional risk factors, such as preterm birth, low birthweight, and lead exposure, among others.

Ninety - nine percent of SIDS infants had at least one intrinsic risk factor (such as male gender or prenatal exposure to cigarettes) or one extrinsic risk factor (such as prone sleep position or soft bedding); 75 percent had at least one of each type of risk factor.

Some risk factors for childhood cancers, including leukemia, have been identified, such as Down syndrome and exposure to ionizing radiation and viruses such as Epstein - Barr virus.

Has other risk factors, including multiple births, exposure to tobacco smoke, exposure to school - aged children, or a family history of asthma

Risk factors included prematurity, prenatal substance exposure, abuse, neglect, or more than one previous placement.

Additionally, in over half of these cases other major risk factors, such as smoke exposure or sleeping on soft surfaces, were present at the death scene.

Mastitis is most common in the first 2 - 3 weeks (as your supply is regulating, etc. as we discussed above), and other risk factors include: cracked nipples (which can cause a portal of entry for bacteria), hospital stay (due to increased risk of exposure to bacteria that could cause harm), previous history of mastitis, weakened immune system, stress and fatigue.

Many of the known risk factors of cancer — all cancers — are the same: smoking or any use of tobacco or nicotine products; exposure to radiation; infection; sunlight; genetic factors; hormones; and aging.

Aside from sleep position, smoke exposure is the largest contributing risk factor for SIDS.149 It is estimated that one - third of SIDS deaths could be prevented if all maternal smoking during pregnancy were eliminated.214, 215 The AAP supports the elimination of all tobacco smoke exposure, both prenatally and environmentally.216, 217

In utero exposure to opiates (primarily methadone and heroin) has been shown in retrospective studies to be associated with an increased risk of SIDS.223, 224 With the exception of 1 study that did not show increased risk, 225 population - based studies have generally shown an increased risk with in utero cocaine exposure.226, — , 228 However, these studies did not control for confounding factors.

Smoke exposure adversely affects infant arousal207, — , 213; in addition, smoke exposure increases risk of preterm birth and low birth weight, both of which are risk factors for SIDS.

The most recent study report described in these same regions decreased tissue levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS risk factors, including tobacco smoking.40 These data confirm results from earlier studies in humans39, 41 and are also consistent with studies in piglets that revealed that postnatal exposure to nicotine decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.

«In traditional risk assessment, we consider apical endpoints and apply safety factors to determine what would be an acceptable level of exposure.

Several genetic and environmental factors, including previous infection with Epstein Barr virus, exposure to cigarette smoke, and low vitamin D levels have all been associated with a heightened risk of MS.

Young horses have higher risk of exposure to these factors because of frequent transport, intense exercise and time spent in stables.

If you are a man and suffer from infertility, you need to consider exposure to environmental pollution as a risk factor.»

Study limitations include that authors were unable to assess certain risk factors for melanoma not captured in the data, including information regarding lifetime sun exposure.

Others have experienced environmental risk factors, such as fetal alcohol exposure, that rule out a simple genetic explanation.

This fashion faded in the 1960s as effective treatments, such as vaccines and antibiotics, became available and people became aware that sun exposure and sunburn during childhood were strong risk factors for developing skin cancer in later life.»

Radiation exposure levels for most people were elevated so minutely above background that it may be impossible to tease out carcinogenic effects from other risk factors, such as smoking or diet.

In addition, the seven - year URECA results confirm previous research linking development of childhood asthma to recognized risk factors such as prenatal exposure to tobacco smoke and maternal stress and depression.

A previous report from URECA that assessed the microbiome of house dust collected in the first year of life suggested that exposure to certain bacteria during infancy may protect 3 - year - olds from recurrent wheezing, a risk factor for developing asthma.

PCBs exposure in Anniston residents under 55 trumped both age and family history as a risk factor for diabetes.

While smoking remains the biggest risk factor for COPD, the study demonstrates that childhood illnesses (such as asthma, bronchitis, pneumonia, allergic rhinitis, eczema) and exposures to parental smoking are also linked to the disease.

Lung function was measured at the ages of 7, 13, 18, 45, 50 and 53 years old, and participants» exposure to various risk factors was also recorded.

The study findings also associate several other factors with an increased risk of developing BD, including preterm birth, head injury, drug exposures (especially cocaine), physical or sexual abuse, and other forms of stress.

One preventable risk factor is ultraviolet exposure from indoor and outdoor tanning.

«One in five Americans will get skin cancer in their lifetime, and sun exposure is the most preventable risk factor for skin cancer,» said Dr. Lim.