Sentences with phrase «risk of metastasis»

If normal, non-cancerous tissue can be seen microscopically and continuously at and around all edges of the removed cancerous mass, the animal has a greatly reduced risk of metastasis from that tumor site.

Unfortunately, the standard tools for assessing risk of metastasis — such as the size of the tumor, its grade, the presence of estrogen receptors and the proportion of dividing cells — are «insufficient,» note the authors, «for clinical decision making.»

Looking at mice with differing risks of metastasis, Kent Hunter at the National Cancer Institute in Bethesda, Maryland, and his team found a circadian rhythm gene, Arntl2, seemed to be involved.

Part of the research is aimed at developing a new prognostic «biomarker» — proteins present in the cancer that identify TNBC patients at high risk of metastasis (development of secondary tumours).

«Urologists tend to prefer to forgo adjuvant radiation therapy, because they fear the side effects, and radiation oncologists tend to prefer offering adjuvant radiation therapy because they fear the risk of metastasis [cancer spreading to other sites in the body],» Showalter said.

The tumor - cell survival factors uncovered by this study might one day be targeted with drugs to further diminish people's risk of metastasis.

«The possibility of preventing or slowing down the spread of cancer cells via the lymphatic system is an attractive one, as it could reduce the risk of metastasis to other organs.»

The risk of metastasis increased to ten percent (13 of 133) in patients with GS 7 disease.

By restoring protein encoded by PARD3 levels, both, cell lines and animal models of mice, we observed that regulating de novo polarization of cells, significantly reduced the risk of metastasis.

But Einstein's Dr. Maja Oktay, a co-author of the new research, cautioned that the typical length of the studies — six or so years — is too short to assess the risk of metastasis, «which can take more than 20 years» to appear, she said.

Using the MACC1 gene as biomarker, physicians can now for the first time determine the risk of metastasis in Klatskin carcinoma.

High or intermediate levels of E-cadherin add little assurance of good prognosis, but abnormally low levels of this protein indicate a substantially increased risk of metastasis.

Tumor location is prognostic in dogs with SCC with evidence of tumor in the tonsils or caudal tongue having a poorer prognosis and increased risk of metastasis.