«At the Comprehensive Transplant Center, we have a commitment to include care for the very sickest, high
risk patients in need of a lifesaving organ transplant.»
Not exact matches
This is the backdrop for The Antidote,
in which Vertex struggles to navigate the FDA's demands for
patient safety, Wall Street's demands for returns, and its own
need to take big bold costly
risks that are likely to end
in failure.
I'm
in a different field, not OB, but if I got a similar question («why do I
need this test or medicine when I have no
risk factors for X and won't it just cause Y problem...») I take the time to talk it through with the
patient.
In addition, the report stresses the
need for
patients to be fully informed of the
risks of treatment at the time of diagnosis, including written information, and psychological support and counselling should be available.
Patients needing special surgery now face the real
risk of dying needlessly because a building
in which their lives would be saved has been under renovation for two years, Dr Hadi Mohammed Abdallah, who speaks for the Specialists, lamented.
«While the small - scale study suggests that beta - blockers may reduce the
risk of breast cancer returning, more research is
needed in this area to determine the effectiveness and safety of the treatment before it can be routinely offered to breast cancer
patients.
Taking antibiotics when they are not
needed creates additional health
risks as it increases the chance a
patient will experience an adverse drug reaction, and also leads to the development of antibiotic - resistant bacteria which affects everyone
in the community.
«The findings suggest the
need for gender - based evaluation and treatment of cardiovascular
risk factors
in these
patients,» says Dr. Farahani.
These findings, which are published
in the Journal of the American Geriatrics Society (JAGS), indicate that efforts to carefully evaluate
risk factors prior to surgery
need more attention, particularly for older minority
patients.
«We wanted to identify
patients at higher
risk for amelanotic melanoma
in whom we
need to look carefully for this cancer type.»
In their article, the authors stressed the
need for clear communication among stakeholders about all the issues they considered, especially so
patients are well - informed about
risks that might not be known yet.
«If the absolute
risk increases of 1.51 percent for
in - hospital mortality and 3.54 percent for major postoperative complications were modifiable, they would be consistent with the number
needed to treat of 59
patients for
in - hospital mortality and 28
patients for major postoperative complications.
In a perspective in this week's New England Journal of Medicine, Daniel Alford, MD, MPH, associate professor of medicine and assistant dean of Continuing Medical Education and director of the Safe and Competent Opioid Prescribing Education (SCOPE of Pain) program at Boston University School of Medicine (BUSM), recommends that prescriber education is the best approach to addressing the prescription opioid - misuse epidemic, allowing for individualized care on the basis of a patient's needs after a careful benefit - risk assessmen
In a perspective
in this week's New England Journal of Medicine, Daniel Alford, MD, MPH, associate professor of medicine and assistant dean of Continuing Medical Education and director of the Safe and Competent Opioid Prescribing Education (SCOPE of Pain) program at Boston University School of Medicine (BUSM), recommends that prescriber education is the best approach to addressing the prescription opioid - misuse epidemic, allowing for individualized care on the basis of a patient's needs after a careful benefit - risk assessmen
in this week's New England Journal of Medicine, Daniel Alford, MD, MPH, associate professor of medicine and assistant dean of Continuing Medical Education and director of the Safe and Competent Opioid Prescribing Education (SCOPE of Pain) program at Boston University School of Medicine (BUSM), recommends that prescriber education is the best approach to addressing the prescription opioid - misuse epidemic, allowing for individualized care on the basis of a
patient's
needs after a careful benefit -
risk assessment.
A study by investigators at Brigham and Women's Hospital (BWH) published this week
in PLOS ONE identifies four factors that may account for sex differences
in statin therapy among
patients with coronary artery disease (CAD), pointing to interventions and additional research that will be
needed to help overcome this sex disparity and reduce cardiovascular
risk for women.
To ensure that
patients can receive all recommended care, we
need to recognize the financial burden of cancer and identify
patients at
risk for financial concerns,» says lead study author Christine M. Veenstra, M.D., M.S.H.P., clinical lecturer
in hematology / oncology at the University of Michigan Medical School.
The more you want to relax your considerations about how close a match you
need with donors, you know, you open up the field of organs that are available for any particular
patient, but you
risk, of course, obviously very, very serious indeed lethal reactions
in most of those cases.
More research, however, is
needed to better characterize those intermediate -
risk patients who can safely be monitored on a surveillance program,» said D. Andrew Loblaw, MD, a radiation oncologist at Sunnybrook Health Sciences Centre
in Toronto, Canada.
A new narrative review authored by Carl Streed Jr., MD, at Brigham and Women's Hospital, published
in the Annals of Internal Medicine, discusses how more research is
needed to better understand cardiovascular disease (CVD) and CVD
risk factors
in transgender
patients receiving long term cross-sex hormone therapy.
A study from Hospital for Special Surgery (HSS) finds that
in morbidly obese
patients, bariatric surgery performed prior to a total hip or knee replacement can reduce
in - hospital and 90 - day postoperative complications and improve
patient health, but it does not reduce the
risk of
needing a revision surgery.
Before undergoing heart imaging procedures involving radiation, healthcare providers should help
patients understand why the procedure is
needed and its potential benefits and
risks, including
risks related to radiation exposure, according to a new scientific statement
in the American Heart Association's journal Circulation.
The authors conclude that recurrence of an atrial tachyarrhythmia was frequent
in both groups, and that when offering ablation as a therapeutic option to
patients with paroxysmal AF who have not previously received antiarrhythmic drugs, the
risks and benefits
need to be discussed and treatment strategy individually recommended.
«
Patients with chronic kidney disease
need to be aware of the potential for higher potassium content
in sodium - reduced foods, as they are educated to follow a low sodium diet and may inadvertently choose sodium - reduced foods without realizing the
risk of an increased potassium load from additives,» she said.
A tool intended to detect signs of autism
in high -
risk infants can be used to help identify and treat
patients with tuberous sclerosis complex (TSC), a genetic disorder, who most
need early intervention.
In the analysis of 23 relevant studies, investigators found that many clinicians are broadly informed about the
risk to their
patients» fertility brought about by cancer treatment, but many factors hinder the appropriate discussions and referrals
needed to provide adequate fertility support to
patients of reproductive age.
Roughly 1
in 5
patients undergoing surgical aortic valve replacement
in the U.S. are estimated to be intermediate -
risk; so together, intermediate - and high -
risk patients comprise the top quartile of all
patients needing an aortic valve replacement.
«There are few other surgical options to reduce the
risk of post-surgery heart damage, meaning new techniques to protect
patients are
needed,» Montaigne said
in a statement.
Gastroenterologists and other health professionals
need to be aware of the increased
risk of cardiovascular diseases, including heart failure,
in their daily handling of
patients with IBD.
Results published
in Hepatology, a journal of the American Association for the Study of Liver Diseases, also found that
patients diagnosed
in childhood were at higher
risk of relapse,
need of a liver transplant, and reduced life expectancy.
Patients diagnosed with autoimmune hepatitis
in childhood had a greater relapse
risk, higher
risk of
needing a liver transplant, and a reduced life expectancy.
«We
need to discover how to make these complex surgeries faster and easier;
in doing so, it will be important to learn as much as possible so that surgeons can tailor the surgical repair to the
patient and balance upfront surgical
risks with improved long - term outcomes,» concluded Dr. Hawkins.
The authors wrote
in their article that «extra consideration will
need to be given to ensure that at -
risk patients can obtain insurance coverage under the ACA.»
«More research is
needed to evaluate the efficacy of this use of a cancer medication to alleviate
risk of sudden cardiac death, but we are hopeful that what we observed
in mice will translate effectively to humans, providing
patients and clinicians with a new paradigm for treating this common and life - threatening illness,» Dudley said.
While Pichia clearly inhibits Candida
in the lab, more work is
needed to tell if a lack of Pichia is the reason HIV
patients are at a higher
risk for thrush.
Our results suggest the
need for future studies involving long - term ambulatory cardiac monitoring to better delineate the
risk associated with transient vs persistent perioperative AF, as well as randomized clinical trials to determine optimal strategies for antithrombotic therapy
in patients with perioperative AF and a significant burden of other
risk factors for stroke,» the authors write.
Many
patients at
risk of transmission, or who
need palliative care, live
in the community because hospitals are full.
Patients in intensive care units (ICUs) may
need to have their lines accessed 20 or more times per day, increasing the
risk for infection and contamination.
«
In light of findings from the study, the dental visit could be a useful opportunity to conduct diabetes screening among at - risk, undiagnosed patients — an important first step in identifying those who need further testing to determine their diabetes status,» said the study's principal investigator, Dr. Shiela Strauss, associate professor of nursing and co-director of the Statistics and Data Management Core for NYU's Colleges of Nursing and Dentistr
In light of findings from the study, the dental visit could be a useful opportunity to conduct diabetes screening among at -
risk, undiagnosed
patients — an important first step
in identifying those who need further testing to determine their diabetes status,» said the study's principal investigator, Dr. Shiela Strauss, associate professor of nursing and co-director of the Statistics and Data Management Core for NYU's Colleges of Nursing and Dentistr
in identifying those who
need further testing to determine their diabetes status,» said the study's principal investigator, Dr. Shiela Strauss, associate professor of nursing and co-director of the Statistics and Data Management Core for NYU's Colleges of Nursing and Dentistry.
«With the aging population, increasing prevalence of co-morbidities and a growing
need for concomitant valve surgery, heart bypass is being performed
in an increasingly high -
risk patient population.
The authors say more
needs to be done to prevent Read more about Dementia
risk higher
in traumatic brain injury
patients - Scimex
Secondly, before considering the use of iPSC - derived organoids for transplantation / regenerative medicine
in human
patients, the current protocols for expansion, reprogramming and differentiation of iPSCs
in long - term cultures
need further improvement to minimize the
risk of oncogenic cellular mutations and teratoma, or tumor formation,
in the
patient.
Kurian, the lead author of the study, said that more genetic counselors are
needed and that doctors should improve their skills
in managing cancer
risk and communicating with
patients.
This model offers unique capabilities for preclinical assessment of thrombosis
risk in a
patient - specific manner, including efficacy testing of anti-thrombotic agents, elucidation of mechanism of action, and, potentially, biomarker identification, all providing a much -
needed platform for drug discovery and development.
Presentations included: Genetics Primer & Clinical Updates by Linford Williams, MS, LGC; Genetics and Women's Health: Seeing and Foreseeing the Ethical Challenges Ahead by Ruth Farrell, MD, MA; Preimplantation Genetic Screening and Diagnosis: What You
Need to Know by Marissa Coleridge, MS, LGC; Evolution of Prenatal Genetic Screening and Testing: NIPT and Beyond by Jeff Chapa, MD, MBA; Promises and Pitfalls of Prenatal Whole Exome Sequencing by Amanda Kalan, MD; Fertility Preservation and Cancer: Survivors, Previvors, and the Newly Diagnosed by Rebecca Flyckt, MD; Improving Access to Cancer Genetics via Telegenetics by Ryan Noss, MS, LGC; Breast Cancer: Management of Moderate Penetrance Predisposition Genes by Holly Pederson, MD; Use of Hormonal and Non-hormonal Therapies
in Breast Cancer Survivors and Women at High
Risk for Breast / Gyn Cancers by Holly Thacker, MD; Addressing Commonly Asked
Patient Questions about Genetics by Rebekah Moore, MS, LGC, Christina Rigelsky, MS, LGC and Allison Schreiber, MS, LGC; and a panel discussion on Genetic Testing Reimbursement featuring Bruce Rogen, MD, MPH and John Yao, MD, MBA, MPH, which was moderated by Daniel Sullivan, MD..
«We
need a range of models to learn about the connections among genes, molecules, cells, synapses and circuits
in normal and abnormal cognition and behavior, and to help us understand the
risks of particular
patients,» says the Broad Institute's Steven Hyman.
Infected
patients are at -
risk for long - term joint stiffness and pain, which increases the
need to better understand the sequence diversity of these viruses and how any viral mutations affect the severity of disease
in the human host.
Their roll - out into translational practice will not be free of complexity, however, as culture and values differ
in terms of what defines benefit and
risk, who will benefit and who is at
risk, what methods must be
in place to assure the maximum safety, comfort, and protection of subjects and
patients, and educational and policy
needs.
Positron emission tomography (PET) imaging of metabolic tumor burden at diagnosis and after induction therapy can help identify
patients most at
risk of follicular lymphoma (FL) recurrence, but more work is
needed to differentiate high -
risk and moderate -
risk patients, suggested findings from a pooled analysis of data from three prospective clinical trials, published
in Blood.
St. Jude Children's Research Hospital investigators report that measuring leukemia cells that persist
in patient bone marrow
in the early weeks of treatment helps identify high -
risk patients who
need intensive therapy.
They have also pulled some
patients away from older systemic (as opposed to topical) drugs often used for moderate - to - severe cases, such as methotrexate and cyclosporine, which
patients sometimes
need to take
in rotation to minimize the
risk of cumulative damage to their organs.
Number 2: They
need to do
risk assessment and management to ensure that the
patient takes the drugs
in a responsible way, and there is minimal
risk of abuse, diversion, and addiction.